BH133_ORYSJ
ID BH133_ORYSJ Reviewed; 198 AA.
AC Q2QQ32; A0A0P0YAL5;
DT 11-DEC-2019, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Transcription factor BHLH133 {ECO:0000305};
DE AltName: Full=Basic helix-loop-helix protein 133 {ECO:0000303|PubMed:16896230};
DE Short=OsbHLH133 {ECO:0000303|PubMed:16896230};
DE AltName: Full=bHLH transcription factor bHLH133 {ECO:0000305};
GN Name=BHLH133 {ECO:0000303|PubMed:16896230};
GN OrderedLocusNames=Os12g0508500 {ECO:0000312|EMBL:BAT17311.1},
GN LOC_Os12g32400 {ECO:0000312|EMBL:ABA99018.1};
GN ORFNames=OsJ_36241 {ECO:0000312|EMBL:EAZ20626.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16896230; DOI=10.1104/pp.106.080580;
RA Li X., Duan X., Jiang H., Sun Y., Tang Y., Yuan Z., Guo J., Liang W.,
RA Chen L., Yin J., Ma H., Wang J., Zhang D.;
RT "Genome-wide analysis of basic/helix-loop-helix transcription factor family
RT in rice and Arabidopsis.";
RL Plant Physiol. 141:1167-1184(2006).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, INDUCTION BY IRON DEIFICIENCY, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=22755510; DOI=10.1111/j.1365-3040.2012.02569.x;
RA Wang L., Ying Y., Narsai R., Ye L., Zheng L., Tian J., Whelan J., Shou H.;
RT "Identification of OsbHLH133 as a regulator of iron distribution between
RT roots and shoots in Oryza sativa.";
RL Plant Cell Environ. 36:224-236(2013).
CC -!- FUNCTION: Transcription factor that acts as regulator of iron
CC homeostasis (PubMed:22755510). May act as negative regulator of iron
CC transportation from root to shoot (PubMed:22755510). Does not seem to
CC be involved in the suppression of the induction of iron deficiency
CC responsive genes (PubMed:22755510). {ECO:0000269|PubMed:22755510}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981,
CC ECO:0000269|PubMed:22755510}.
CC -!- INDUCTION: Strongly induced by iron deficiency in roots
CC (PubMed:22755510). Slightly induced in shoots (PubMed:22755510).
CC {ECO:0000269|PubMed:22755510}.
CC -!- DISRUPTION PHENOTYPE: Slight reduction of shoot length and 2-fold
CC reduction of seed set. {ECO:0000269|PubMed:22755510}.
CC -!- MISCELLANEOUS: Plants overexpressing BHLH133 are hypersensitive to iron
CC deficiency. {ECO:0000269|PubMed:22755510}.
CC -!- SIMILARITY: Belongs to the bHLH protein family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAT17311.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DP000011; ABA99018.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT17311.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM000149; EAZ20626.1; -; Genomic_DNA.
DR RefSeq; XP_015619477.1; XM_015763991.1.
DR AlphaFoldDB; Q2QQ32; -.
DR SMR; Q2QQ32; -.
DR STRING; 39947.Q2QQ32; -.
DR GeneID; 107276670; -.
DR OrthoDB; 987931at2759; -.
DR Proteomes; UP000007752; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IC:Gramene.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IC:Gramene.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..198
FT /note="Transcription factor BHLH133"
FT /id="PRO_0000448626"
FT DOMAIN 114..163
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 114..127
FT /note="Basic motif; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 128..163
FT /note="Helix-loop-helix motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ SEQUENCE 198 AA; 22598 MW; 8CEEDD88CB41835B CRC64;
MECSSFEAIC NESEMIAHLQ SLFWSSSDAD PCFGSSSFSL ISSEGYDTMT TEFVNSSTNV
CFDYQDDSFV SAEETTIGNK RKVQMDTENE LMTNRSKEVR TKMSVSKACK HSVSAESSQS
YYAKNRRQRI NERLRILQEL IPNGTKVDIS TMLEEAIQYV KFLHLQIKLL SSDEMWMYAP
LAFDSGNNRL YQNSLSQE
