BH137_ARATH
ID BH137_ARATH Reviewed; 286 AA.
AC Q93W88;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Transcription factor bHLH137;
DE AltName: Full=Basic helix-loop-helix protein 137;
DE Short=AtbHLH137;
DE Short=bHLH 137;
DE AltName: Full=Transcription factor EN 89;
DE AltName: Full=bHLH transcription factor bHLH137;
GN Name=BHLH137; Synonyms=EN89; OrderedLocusNames=At5g50915; ORFNames=K3K7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q93W88; Q9LV17: BHLH79; NbExp=3; IntAct=EBI-15198405, EBI-15191993;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
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DR EMBL; AB017063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED96009.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96010.1; -; Genomic_DNA.
DR EMBL; AF428350; AAL16280.1; -; mRNA.
DR EMBL; AY057549; AAL09788.1; -; mRNA.
DR EMBL; AY113059; AAM47367.1; -; mRNA.
DR EMBL; AY087602; AAM65144.1; -; mRNA.
DR RefSeq; NP_568745.1; NM_124470.3.
DR RefSeq; NP_851163.1; NM_180832.3.
DR AlphaFoldDB; Q93W88; -.
DR SMR; Q93W88; -.
DR BioGRID; 20410; 36.
DR IntAct; Q93W88; 36.
DR STRING; 3702.AT5G50915.1; -.
DR PaxDb; Q93W88; -.
DR PRIDE; Q93W88; -.
DR EnsemblPlants; AT5G50915.1; AT5G50915.1; AT5G50915.
DR EnsemblPlants; AT5G50915.2; AT5G50915.2; AT5G50915.
DR GeneID; 835164; -.
DR Gramene; AT5G50915.1; AT5G50915.1; AT5G50915.
DR Gramene; AT5G50915.2; AT5G50915.2; AT5G50915.
DR KEGG; ath:AT5G50915; -.
DR Araport; AT5G50915; -.
DR TAIR; locus:505006688; AT5G50915.
DR eggNOG; ENOG502R2X6; Eukaryota.
DR HOGENOM; CLU_061056_0_0_1; -.
DR InParanoid; Q93W88; -.
DR OMA; IIVRPEM; -.
DR OrthoDB; 1291129at2759; -.
DR PhylomeDB; Q93W88; -.
DR PRO; PR:Q93W88; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q93W88; baseline and differential.
DR Genevisible; Q93W88; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0071368; P:cellular response to cytokinin stimulus; IEP:TAIR.
DR GO; GO:0042127; P:regulation of cell population proliferation; IDA:TAIR.
DR GO; GO:0009739; P:response to gibberellin; IEP:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR024097; bHLH_ZIP_TF.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR12565; PTHR12565; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..286
FT /note="Transcription factor bHLH137"
FT /id="PRO_0000358818"
FT DOMAIN 142..192
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 63..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 31773 MW; 442C97DB30EB1278 CRC64;
MATFSYFQNY PHSLLDPLLF PTPHSSINLT SFIDQNHLYP LPNISTVEDI SFLEYNVDKT
ENSGSEKLAN TTKTATTGSS SCDQLSHGPS AITNTGKTRG RKARNSNNSK EGVEGRKSKK
QKRGSKEEPP TDYIHVRARR GQATDSHSLA ERVRREKISE RMRTLQNLVP GCDKVTGKAL
MLDEIINYVQ TLQTQVEFLS MKLTSISPVV YDFGSDLDGL ILQSEMGSPE VGTSFTNAMP
TTTPIFPSLL DNSVVPTHAQ VQEEGEEREN FVDRSGFNNN NFCSFP
