BH139_ARATH
ID BH139_ARATH Reviewed; 223 AA.
AC Q3E7L7;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Transcription factor bHLH139;
DE AltName: Full=Basic helix-loop-helix protein 139;
DE Short=AtbHLH139;
DE Short=bHLH 139;
DE AltName: Full=Transcription factor EN 116;
DE AltName: Full=bHLH transcription factor bHLH139;
GN Name=BHLH139; Synonyms=EN116; OrderedLocusNames=At5g43175; ORFNames=MMG4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
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DR EMBL; AB008267; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED94919.1; -; Genomic_DNA.
DR RefSeq; NP_680385.1; NM_148080.2.
DR AlphaFoldDB; Q3E7L7; -.
DR SMR; Q3E7L7; -.
DR BioGRID; 19585; 2.
DR STRING; 3702.AT5G43175.1; -.
DR PaxDb; Q3E7L7; -.
DR PRIDE; Q3E7L7; -.
DR EnsemblPlants; AT5G43175.1; AT5G43175.1; AT5G43175.
DR GeneID; 834335; -.
DR Gramene; AT5G43175.1; AT5G43175.1; AT5G43175.
DR KEGG; ath:AT5G43175; -.
DR Araport; AT5G43175; -.
DR TAIR; locus:504954900; AT5G43175.
DR eggNOG; ENOG502RRIG; Eukaryota.
DR HOGENOM; CLU_1241620_0_0_1; -.
DR InParanoid; Q3E7L7; -.
DR OMA; MYAPLAH; -.
DR OrthoDB; 987931at2759; -.
DR PhylomeDB; Q3E7L7; -.
DR PRO; PR:Q3E7L7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q3E7L7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..223
FT /note="Transcription factor bHLH139"
FT /id="PRO_0000358819"
FT DOMAIN 138..187
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 64..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 223 AA; 25076 MW; 092AB779C68B79FD CRC64;
MENEAFVDGE LESLLGMFNF DQCSSNESSF CNAPNETDVF SSDDFFPFGT ILQSNYAAVL
DGSNHQTNRN VDSRQDLLKP RKKQKLSSES NLVTEPKTAW RDGQSLSSYN SSDDEKALGL
VSNTSKSLKR KAKANRGIAS DPQSLYARKR RERINDRLKT LQSLVPNGTK VDISTMLEDA
VHYVKFLQLQ IKLLSSEDLW MYAPLAHNGL NMGLHHNLLS RLI
