BH143_ARATH
ID BH143_ARATH Reviewed; 326 AA.
AC Q9FY69;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Transcription factor bHLH143;
DE AltName: Full=Basic helix-loop-helix protein 143;
DE Short=AtbHLH143;
DE Short=bHLH 143;
DE AltName: Full=Transcription factor EN 129;
DE AltName: Full=bHLH transcription factor bHLH143;
GN Name=BHLH143; Synonyms=EN129; OrderedLocusNames=At5g09460;
GN ORFNames=T5E8.260;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q9FY69; Q58G01: BHLH155; NbExp=3; IntAct=EBI-15194247, EBI-15197899;
CC Q9FY69; Q7XJU0-2: BHLH157; NbExp=3; IntAct=EBI-15194247, EBI-15196985;
CC Q9FY69; Q8S3D2: BHLH87; NbExp=3; IntAct=EBI-15194247, EBI-15194565;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
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DR EMBL; AL391712; CAC05472.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91396.1; -; Genomic_DNA.
DR EMBL; AY128339; AAM91542.1; -; mRNA.
DR EMBL; BT000009; AAN15328.1; -; mRNA.
DR RefSeq; NP_196508.1; NM_120983.2.
DR AlphaFoldDB; Q9FY69; -.
DR SMR; Q9FY69; -.
DR BioGRID; 16083; 23.
DR IntAct; Q9FY69; 22.
DR STRING; 3702.AT5G09460.1; -.
DR PaxDb; Q9FY69; -.
DR PRIDE; Q9FY69; -.
DR EnsemblPlants; AT5G09460.1; AT5G09460.1; AT5G09460.
DR GeneID; 830805; -.
DR Gramene; AT5G09460.1; AT5G09460.1; AT5G09460.
DR KEGG; ath:AT5G09460; -.
DR Araport; AT5G09460; -.
DR TAIR; locus:2184822; AT5G09460.
DR eggNOG; ENOG502S1PH; Eukaryota.
DR HOGENOM; CLU_053960_0_0_1; -.
DR InParanoid; Q9FY69; -.
DR OMA; YLQPPFQ; -.
DR OrthoDB; 1201232at2759; -.
DR PhylomeDB; Q9FY69; -.
DR PRO; PR:Q9FY69; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FY69; baseline and differential.
DR Genevisible; Q9FY69; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR037546; SAC51-like.
DR PANTHER; PTHR36066; PTHR36066; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..326
FT /note="Transcription factor bHLH143"
FT /id="PRO_0000358821"
FT DOMAIN 263..312
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 175..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 326 AA; 36444 MW; CD25D71F834FCC2C CRC64;
MPLDTKQQKW LPLGLNPQAC VQDKATEYFR PGIPFPELGK VYAAEHQFRY LQPPFQALLS
RYDQQSCGKQ VSCLNGRSSN GAAPEGALKS SRKRFIVFDQ SGEQTRLLQC GFPLRFPSSM
DAERGNILGA LHPEKGFSKD HAIQEKILQH EDHENGEEDS EMHEDTEEIN ALLYSDDDDN
DDWESDDEVM STGHSPFTVE QQACNITTEE LDETESTVDG PLLKRQKLLD HSYRDSSPSL
VGTTKVKGLS DENLPESNIS SKQETGSGLS DEQSRKDKIH TALRILESVV PGAKGKEALL
LLDEAIDYLK LLKQSLNSSK GLNNHW
