BH145_ARATH
ID BH145_ARATH Reviewed; 311 AA.
AC Q9FGB0;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Transcription factor bHLH145;
DE AltName: Full=Basic helix-loop-helix protein 145;
DE Short=AtbHLH145;
DE Short=bHLH 145;
DE AltName: Full=Transcription factor EN 131;
DE AltName: Full=bHLH transcription factor bHLH145;
GN Name=BHLH145; Synonyms=EN131; OrderedLocusNames=At5g50010;
GN ORFNames=MPF21.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q9FGB0; Q9ASX9: BHLH144; NbExp=3; IntAct=EBI-4477059, EBI-15195383;
CC Q9FGB0; Q58G01: BHLH155; NbExp=3; IntAct=EBI-4477059, EBI-15197899;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
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DR EMBL; AB026650; BAB10287.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95883.1; -; Genomic_DNA.
DR EMBL; AK117155; BAC41833.1; -; mRNA.
DR EMBL; BT005301; AAO63365.1; -; mRNA.
DR RefSeq; NP_199812.1; NM_124380.3.
DR AlphaFoldDB; Q9FGB0; -.
DR SMR; Q9FGB0; -.
DR BioGRID; 20311; 16.
DR IntAct; Q9FGB0; 16.
DR STRING; 3702.AT5G50010.1; -.
DR PaxDb; Q9FGB0; -.
DR PRIDE; Q9FGB0; -.
DR EnsemblPlants; AT5G50010.1; AT5G50010.1; AT5G50010.
DR GeneID; 835065; -.
DR Gramene; AT5G50010.1; AT5G50010.1; AT5G50010.
DR KEGG; ath:AT5G50010; -.
DR Araport; AT5G50010; -.
DR TAIR; locus:2170111; AT5G50010.
DR eggNOG; ENOG502R77Z; Eukaryota.
DR HOGENOM; CLU_895306_0_0_1; -.
DR InParanoid; Q9FGB0; -.
DR OMA; CPDMKEE; -.
DR OrthoDB; 792057at2759; -.
DR PhylomeDB; Q9FGB0; -.
DR PRO; PR:Q9FGB0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGB0; baseline and differential.
DR Genevisible; Q9FGB0; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR037546; SAC51-like.
DR PANTHER; PTHR36066; PTHR36066; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..311
FT /note="Transcription factor bHLH145"
FT /id="PRO_0000358823"
FT DOMAIN 253..302
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ SEQUENCE 311 AA; 34714 MW; 70CB6F35B641F22A CRC64;
MGQDRGFGFP TQRLCSLSSL ALSHLGKQDL NLVSKTCGDT TDMFSTRGSY QVSTQVSQSY
FDGYCGWVHG SSHLQQQFLP PQNQCMKQVP LQVDGVISKA EEQCSQKRFL VFDQSGDQTT
LLLASDIRKS FETLKQHACP DMKEELQRSN KDLFVCHGMQ GNSEPDLKED SEELNALLYS
EDESGYCSEE DEVTSADHSP SIVVSGREDQ KTFLGSYGQP LNAKKRKILE TSNESMRDAE
SSCGSCDNTR ISFLKRSKLS SNKIGEEKIF ETVSLLRSVV PGEELVDPIL VIDRAIDYLK
SLKMEAKNRE A