BH147_ARATH
ID BH147_ARATH Reviewed; 230 AA.
AC Q9LSN7;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Transcription factor bHLH147;
DE AltName: Full=ATBS1 interacting factor 3;
DE AltName: Full=Basic helix-loop-helix protein 147;
DE Short=AtbHLH147;
DE Short=bHLH 147;
DE AltName: Full=Transcription factor EN 142;
DE AltName: Full=bHLH transcription factor bHLH147;
GN Name=BHLH147; Synonyms=AIF3, EN142; OrderedLocusNames=At3g17100;
GN ORFNames=K14A17.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
RN [7]
RP FUNCTION, AND INTERACTION WITH PRE3.
RC STRAIN=cv. Columbia;
RX PubMed=20023194; DOI=10.1105/tpc.109.072504;
RA Wang H., Zhu Y., Fujioka S., Asami T., Li J., Li J.;
RT "Regulation of Arabidopsis brassinosteroid signaling by atypical basic
RT helix-loop-helix proteins.";
RL Plant Cell 21:3781-3791(2009).
CC -!- FUNCTION: Atypical bHLH transcription factor probably unable to bind
CC DNA. Negatively regulates brassinosteroid signaling.
CC {ECO:0000269|PubMed:20023194}.
CC -!- SUBUNIT: Homodimer (Probable). Interacts with PRE3.
CC {ECO:0000269|PubMed:20023194, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB026636; BAA94988.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75904.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75905.1; -; Genomic_DNA.
DR EMBL; AY045684; AAK74042.1; -; mRNA.
DR EMBL; AY057736; AAL15366.1; -; mRNA.
DR EMBL; AK230300; BAF02101.1; -; mRNA.
DR RefSeq; NP_566567.1; NM_112586.3.
DR RefSeq; NP_850601.1; NM_180270.3.
DR AlphaFoldDB; Q9LSN7; -.
DR SMR; Q9LSN7; -.
DR STRING; 3702.AT3G17100.1; -.
DR PaxDb; Q9LSN7; -.
DR PRIDE; Q9LSN7; -.
DR EnsemblPlants; AT3G17100.1; AT3G17100.1; AT3G17100.
DR EnsemblPlants; AT3G17100.2; AT3G17100.2; AT3G17100.
DR GeneID; 820967; -.
DR Gramene; AT3G17100.1; AT3G17100.1; AT3G17100.
DR Gramene; AT3G17100.2; AT3G17100.2; AT3G17100.
DR KEGG; ath:AT3G17100; -.
DR Araport; AT3G17100; -.
DR TAIR; locus:2086117; AT3G17100.
DR eggNOG; ENOG502RY2C; Eukaryota.
DR HOGENOM; CLU_090794_0_1_1; -.
DR InParanoid; Q9LSN7; -.
DR OMA; HEEGQTH; -.
DR OrthoDB; 1412976at2759; -.
DR PhylomeDB; Q9LSN7; -.
DR PRO; PR:Q9LSN7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LSN7; baseline and differential.
DR Genevisible; Q9LSN7; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd11444; bHLH_AtIBH1_like; 1.
DR InterPro; IPR044549; bHLH_AtIBH1-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR044660; IBH1-like.
DR PANTHER; PTHR33124; PTHR33124; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..230
FT /note="Transcription factor bHLH147"
FT /id="PRO_0000358824"
FT DOMAIN 147..196
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 230 AA; 25311 MW; 59123B68F7BDA739 CRC64;
MESISPVSNQ LLQPTTTSSN SDRSRRKRKK KSSPSSVEKS PSPSISLEKW RSEKQQQIYS
TKLVHALREL RISQQPSSSS SSSIPRGGRA VREVADRALA VAARGKTLWS RAILSKAVKL
KFRKHKRQRI SNPTTTTLTT GSIRSKKQRA TVLRLKAKGL PAVQRKVKVL SRLVPGCRKQ
SLPVVLEETT DYIAAMEMQI RTMTAILSAV SSSPPPPTPG HEGGQTHMLG
