ID   SIRB1_ECOLI             Reviewed;         269 AA.
AC   P0AGM5; P20101; P76020; Q9R325;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=UPF0162 protein YchA;
DE   AltName: Full=Protein SirB1;
GN   Name=ychA; Synonyms=sirB1; OrderedLocusNames=b1214, JW1205;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=7543480; DOI=10.1128/jb.177.15.4488-4500.1995;
RA   Strohmaier H., Remler P., Renner W., Hoegenauer G.;
RT   "Expression of genes kdsA and kdsB involved in 3-deoxy-D-manno-octulosonic
RT   acid metabolism and biosynthesis of enterobacterial lipopolysaccharide is
RT   growth phase regulated primarily at the transcriptional level in
RT   Escherichia coli K-12.";
RL   J. Bacteriol. 177:4488-4500(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-206.
RC   STRAIN=K12;
RX   PubMed=7883187; DOI=10.1016/0378-1119(94)00805-3;
RA   Nakayashiki T., Nishimura K., Inokuchi H.;
RT   "Cloning and sequencing of a previously unidentified gene that is involved
RT   in the biosynthesis of heme in Escherichia coli.";
RL   Gene 153:67-70(1995).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 124-269.
RX   PubMed=3039295; DOI=10.1007/bf00331603;
RA   Woisetschlaeger M., Hoegenauer G.;
RT   "The kdsA gene coding for 3-deoxy-D-manno-octulosonic acid 8-phosphate
RT   synthetase is part of an operon in Escherichia coli.";
RL   Mol. Gen. Genet. 207:369-373(1987).
CC   -!- SIMILARITY: Belongs to the UPF0162 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA05916.1; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U18555; AAC43440.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC74298.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA36072.1; -; Genomic_DNA.
DR   EMBL; D28567; BAA05916.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; X05552; CAA29066.1; -; Genomic_DNA.
DR   PIR; I83572; I83572.
DR   RefSeq; NP_415732.1; NC_000913.3.
DR   RefSeq; WP_001257044.1; NZ_STEB01000023.1.
DR   AlphaFoldDB; P0AGM5; -.
DR   SMR; P0AGM5; -.
DR   BioGRID; 4260115; 14.
DR   DIP; DIP-35939N; -.
DR   IntAct; P0AGM5; 5.
DR   STRING; 511145.b1214; -.
DR   PaxDb; P0AGM5; -.
DR   PRIDE; P0AGM5; -.
DR   EnsemblBacteria; AAC74298; AAC74298; b1214.
DR   EnsemblBacteria; BAA36072; BAA36072; BAA36072.
DR   GeneID; 66674966; -.
DR   GeneID; 945784; -.
DR   KEGG; ecj:JW1205; -.
DR   KEGG; eco:b1214; -.
DR   PATRIC; fig|511145.12.peg.1262; -.
DR   EchoBASE; EB1231; -.
DR   eggNOG; COG2912; Bacteria.
DR   HOGENOM; CLU_063810_0_0_6; -.
DR   InParanoid; P0AGM5; -.
DR   OMA; LWIAAEH; -.
DR   PhylomeDB; P0AGM5; -.
DR   BioCyc; EcoCyc:EG11251-MON; -.
DR   PRO; PR:P0AGM5; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   InterPro; IPR032698; SirB1_N.
DR   Pfam; PF13369; Transglut_core2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..269
FT                   /note="UPF0162 protein YchA"
FT                   /id="PRO_0000202377"
SQ   SEQUENCE   269 AA;  30841 MW;  B7EEAC15FE3BD763 CRC64;
     MRSLADFEFN KAPLCEGMIL ACEAIRRDFP SQDVYDELER LVSLAKEEIS QLLPLEEQLE
     KLIALFYGDW GFKASRGVYR LSDALWLDQV LKNRQGSAVS LGAVLLWVAN RLDLPLLPVI
     FPTQLILRIE CPDGEIWLIN PFNGESLSEH MLDVWLKGNI SPSAELFYED LDEADNIEVI
     RKLLDTLKAS LMEENQMELA LRTSEALLQF NPEDPYEIRD RGLIYAQLDC EHVALNDLSY
     FVEQCPEDPI SEMIRAQINN IAHKHIVLH