SIRB2_ECOLI
ID SIRB2_ECOLI Reviewed; 130 AA.
AC Q46755;
DT 27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Protein YchQ;
DE AltName: Full=Protein SirB2;
GN Name=ychQ; Synonyms=sirB2; OrderedLocusNames=b1213, JW1204;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7543480; DOI=10.1128/jb.177.15.4488-4500.1995;
RA Strohmaier H., Remler P., Renner W., Hoegenauer G.;
RT "Expression of genes kdsA and kdsB involved in 3-deoxy-D-manno-octulosonic
RT acid metabolism and biosynthesis of enterobacterial lipopolysaccharide is
RT growth phase regulated primarily at the transcriptional level in
RT Escherichia coli K-12.";
RL J. Bacteriol. 177:4488-4500(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP SUBCELLULAR LOCATION, AND TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000305|PubMed:15919996}.
CC -!- SIMILARITY: Belongs to the SirB2 family. {ECO:0000305}.
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DR EMBL; U18555; AAC43439.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74297.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA36071.1; -; Genomic_DNA.
DR PIR; I83571; I83571.
DR RefSeq; NP_415731.1; NC_000913.3.
DR RefSeq; WP_000200374.1; NZ_SSZK01000010.1.
DR AlphaFoldDB; Q46755; -.
DR SMR; Q46755; -.
DR BioGRID; 4263203; 9.
DR IntAct; Q46755; 1.
DR STRING; 511145.b1213; -.
DR PaxDb; Q46755; -.
DR PRIDE; Q46755; -.
DR EnsemblBacteria; AAC74297; AAC74297; b1213.
DR EnsemblBacteria; BAA36071; BAA36071; BAA36071.
DR GeneID; 945781; -.
DR KEGG; ecj:JW1204; -.
DR KEGG; eco:b1213; -.
DR PATRIC; fig|1411691.4.peg.1071; -.
DR EchoBASE; EB4041; -.
DR eggNOG; COG3094; Bacteria.
DR HOGENOM; CLU_123860_3_0_6; -.
DR InParanoid; Q46755; -.
DR OMA; WVVYAAK; -.
DR PhylomeDB; Q46755; -.
DR BioCyc; EcoCyc:G6630-MON; -.
DR PRO; PR:Q46755; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR InterPro; IPR007360; SirB.
DR PANTHER; PTHR39594; PTHR39594; 1.
DR Pfam; PF04247; SirB; 1.
DR PIRSF; PIRSF005610; SirB; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..130
FT /note="Protein YchQ"
FT /id="PRO_0000097770"
FT TOPO_DOM 1..9
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 10..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..39
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 60..73
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 94..104
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 125..130
FT /note="Periplasmic"
FT /evidence="ECO:0000255, ECO:0000269|PubMed:15919996"
SQ SEQUENCE 130 AA; 14639 MW; 56A2D27776F44238 CRC64;
MTSFSTLLSV HLISIALSVG LLTLRFWLRY QKHPQAFARW TRIVPPVVDT LLLLSGIALM
AKAHILPFSG QAQWLTEKLF GVIIYIVLGF IALDYRRMHS QQARIIAFPL ALVVLYIIIK
LATTKVPLLG
