BH156_ORYSJ
ID BH156_ORYSJ Reviewed; 352 AA.
AC A0A0N7KIY3; Q7XVB7;
DT 11-DEC-2019, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2016, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Transcription factor BHLH156 {ECO:0000305};
DE AltName: Full=Basic helix-loop-helix protein 156 {ECO:0000303|PubMed:16896230};
DE Short=OsbHLH156 {ECO:0000303|PubMed:16896230};
DE AltName: Full=bHLH transcription factor bHLH156 {ECO:0000305};
GN Name=BHLH156 {ECO:0000303|PubMed:16896230};
GN OrderedLocusNames=Os04g0381700 {ECO:0000312|EMBL:BAS88897.1},
GN LOC_Os04g31290 {ECO:0000305};
GN ORFNames=OSJNBa0072D21.7 {ECO:0000312|EMBL:CAD40741.2};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16896230; DOI=10.1104/pp.106.080580;
RA Li X., Duan X., Jiang H., Sun Y., Tang Y., Yuan Z., Guo J., Liang W.,
RA Chen L., Yin J., Ma H., Wang J., Zhang D.;
RT "Genome-wide analysis of basic/helix-loop-helix transcription factor family
RT in rice and Arabidopsis.";
RL Plant Physiol. 141:1167-1184(2006).
RN [5]
RP FUNCTION, HOMODIMERIZATION, INTERACTION WITH IRO2, SUBCELLULAR LOCATION,
RP TISSUE SPECIFICITY, INDUCTION BY IRON DEFICIENCY, AND DISRUPTION PHENOTYPE.
RX PubMed=31574173; DOI=10.1111/nph.16232;
RA Wang S., Li L., Ying Y., Wang J., Shao J.F., Yamaji N., Whelan J., Ma J.F.,
RA Shou H.;
RT "A transcription factor OsbHLH156 regulates Strategy II iron acquisition
RT through localizing IRO2 to the nucleus in rice.";
RL New Phytol. 225:1247-1260(2020).
CC -!- FUNCTION: Transcription factor involved in positive regulation of genes
CC involved in strategy II iron acquisition, including genes for mugineic
CC acid (MA) family phytosiderophores biosynthesis, and genes involved in
CC S-adenosylmethionine cycle and iron transport (PubMed:31574173). May
CC play a role in the regulation of iron deficiency response by promoting
CC the nuclear localization of IRO2 (PubMed:31574173). Possesses
CC transactivation activity in yeast (PubMed:31574173).
CC {ECO:0000269|PubMed:31574173}.
CC -!- SUBUNIT: Forms homodimers (PubMed:31574173). Interacts with IRO2 in the
CC nucleus (PubMed:31574173). {ECO:0000269|PubMed:31574173}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981,
CC ECO:0000269|PubMed:31574173}.
CC -!- TISSUE SPECIFICITY: Expressed in the meristematic zone of lateral and
CC primary roots. {ECO:0000269|PubMed:31574173}.
CC -!- INDUCTION: Strongly induced by iron deficiency in roots, but not in
CC shoots. {ECO:0000269|PubMed:31574173}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but mutant plants exhibit impaired growth, leaf chlorosis
CC and reduced iron concentration in shoots, when grown under iron
CC deficiency conditions. {ECO:0000269|PubMed:31574173}.
CC -!- SIMILARITY: Belongs to the bHLH protein family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAD40741.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL662977; CAD40741.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014960; BAS88897.1; -; Genomic_DNA.
DR RefSeq; XP_015634338.1; XM_015778852.1.
DR AlphaFoldDB; A0A0N7KIY3; -.
DR SMR; A0A0N7KIY3; -.
DR STRING; 4530.OS04T0381700-00; -.
DR PaxDb; A0A0N7KIY3; -.
DR EnsemblPlants; Os04t0381700-00; Os04t0381700-00; Os04g0381700.
DR GeneID; 107276663; -.
DR Gramene; Os04t0381700-00; Os04t0381700-00; Os04g0381700.
DR KEGG; osa:107276663; -.
DR eggNOG; ENOG502QSJP; Eukaryota.
DR OMA; DRMQEWQ; -.
DR OrthoDB; 1358513at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..352
FT /note="Transcription factor BHLH156"
FT /id="PRO_0000448625"
FT DOMAIN 130..179
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 59..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..143
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 144..179
FT /note="Helix-loop-helix motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 194..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 36814 MW; 8F7437631ACA8181 CRC64;
MEHHHLLLQL SPPPPPPPLP AAHLMMSPSF FDAGVFADVG GDWMEDLMHL GELFGVGVGG
DDDDNGGVDG GVGGGDDRMQ EWQNNCEGAG SPDHQPSCGD GDGDGDGDVS PRDGELGDGD
GDNSATRKRR DRSKTIVSER KRRVRMKEKL YELRALVPNI TKMDKASIIA DAVVYVKDLQ
AHARKLKEEV AALEEARPIR PPPPSAAAQR PQRQPRRVAA AAAQLARAAD AAAVTTAAAA
PHGARVAHVG AAQVGEGRFF VTVECEPAAA AARGGGGGVA APVCAAVESL SCFTVESSTV
GCSPDRVVAT LTLKVSEAEE DVSAISECTV KLWVMAALLK EGFRPQPTVQ IS
