BH160_ARATH
ID BH160_ARATH Reviewed; 234 AA.
AC F4I8F9; Q9C988;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Transcription factor bHLH160;
DE AltName: Full=Basic helix-loop-helix protein 160;
DE Short=AtbHLH160 {ECO:0000303|PubMed:14600211};
DE Short=bHLH 160;
DE AltName: Full=bHLH transcription factor bHLH160;
GN Name=BHLH160 {ECO:0000303|PubMed:14600211};
GN OrderedLocusNames=At1g71200 {ECO:0000312|Araport:AT1G71200};
GN ORFNames=F23N20.19 {ECO:0000312|EMBL:AAG51686.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- SIMILARITY: Belongs to the bHLH protein family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51686.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC016972; AAG51686.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE35172.1; -; Genomic_DNA.
DR RefSeq; NP_177276.4; NM_105789.5.
DR AlphaFoldDB; F4I8F9; -.
DR SMR; F4I8F9; -.
DR STRING; 3702.AT1G71200.1; -.
DR iPTMnet; F4I8F9; -.
DR PaxDb; F4I8F9; -.
DR PRIDE; F4I8F9; -.
DR EnsemblPlants; AT1G71200.1; AT1G71200.1; AT1G71200.
DR GeneID; 843460; -.
DR Gramene; AT1G71200.1; AT1G71200.1; AT1G71200.
DR KEGG; ath:AT1G71200; -.
DR Araport; AT1G71200; -.
DR TAIR; locus:2026291; AT1G71200.
DR eggNOG; ENOG502S1VN; Eukaryota.
DR HOGENOM; CLU_101542_0_0_1; -.
DR InParanoid; F4I8F9; -.
DR OMA; FHFEMMF; -.
DR PRO; PR:F4I8F9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I8F9; baseline and differential.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0071280; P:cellular response to copper ion; IMP:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR015660; MASH1/Ascl1a-like.
DR PANTHER; PTHR13935; PTHR13935; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..234
FT /note="Transcription factor bHLH160"
FT /id="PRO_0000439393"
FT DOMAIN 60..115
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 234 AA; 26390 MW; 03D1915A3536B7DA CRC64;
MSSQPNHQTS ISSLLHDRLH IPPAETIVEK ESAEKDTCQS QRKRKEPVLH EVDGSSSGAA
KKQDHNAKER LRRMRLHASY LTLGTLLPDH SSSSSKKKWS APSIIDNVIT YIPKLQNEVG
ELTLRKQKLV ELERRGPSIR AISVLELGES GYEAVVQICL KKENEDEFSN LLHVMEVQGL
SVLSASTSQV CREQRVVCYN FHVKMDEKPC EGDDYITVLK NNIISSLRDN TKCK
