ID   BH168_ARATH             Reviewed;         174 AA.
AC   Q9XIJ1;
DT   12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 129.
DE   RecName: Full=Transcription factor bHLH168 {ECO:0000305};
DE   AltName: Full=Basic helix-loop-helix protein 168 {ECO:0000305};
DE            Short=AtbHLH168 {ECO:0000305};
DE            Short=bHLH 168 {ECO:0000305};
DE   AltName: Full=bHLH transcription factor bHLH168 {ECO:0000305};
GN   Name=BHLH168 {ECO:0000305};
GN   OrderedLocusNames=At1g10586 {ECO:0000312|Araport:AT1G10586};
GN   ORFNames=T10O24.23 {ECO:0000312|EMBL:AAD39583.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences. {ECO:0000305};
CC       Name=1;
CC         IsoId=Q9XIJ1-1; Sequence=Displayed;
CC   -!- SIMILARITY: Belongs to the bHLH protein family. {ECO:0000305}.
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DR   EMBL; AC007067; AAD39583.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE28599.1; -; Genomic_DNA.
DR   PIR; D86239; D86239.
DR   RefSeq; NP_001117258.1; NM_001123786.1. [Q9XIJ1-1]
DR   AlphaFoldDB; Q9XIJ1; -.
DR   SMR; Q9XIJ1; -.
DR   IntAct; Q9XIJ1; 12.
DR   STRING; 3702.AT1G10586.1; -.
DR   PaxDb; Q9XIJ1; -.
DR   PRIDE; Q9XIJ1; -.
DR   EnsemblPlants; AT1G10586.1; AT1G10586.1; AT1G10586. [Q9XIJ1-1]
DR   GeneID; 6240488; -.
DR   Gramene; AT1G10586.1; AT1G10586.1; AT1G10586. [Q9XIJ1-1]
DR   KEGG; ath:AT1G10586; -.
DR   Araport; AT1G10586; -.
DR   TAIR; locus:4515102513; AT1G10586.
DR   eggNOG; ENOG502STRJ; Eukaryota.
DR   HOGENOM; CLU_083174_4_0_1; -.
DR   InParanoid; Q9XIJ1; -.
DR   OMA; VYYTIHA; -.
DR   OrthoDB; 1397684at2759; -.
DR   PhylomeDB; Q9XIJ1; -.
DR   PRO; PR:Q9XIJ1; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9XIJ1; baseline and differential.
DR   GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR015660; MASH1/Ascl1a-like.
DR   PANTHER; PTHR13935; PTHR13935; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   3: Inferred from homology;
KW   Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..174
FT                   /note="Transcription factor bHLH168"
FT                   /id="PRO_0000439396"
FT   DOMAIN          14..63
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ   SEQUENCE   174 AA;  20083 MW;  F9F7563359FC628E CRC64;
     MERAREIGEG SASSLREQRN LREKERRMRM KHLFSILSSH VSPTRRLPVP QLIDQAVSYM
     IQLKEKVNYL NEMKRRMLGG EVKNRSEGSS LLPKLSIRSL DSIIEMNLVM DLNMKGVMLH
     KLVSVFEEEG AQVMSANLQN LNDRTFYTII AQAIICRIGI DPSRIEERLR DIIS