ID   SJ381_SCHJA             Reviewed;         150 AA.
AC   Q5C6R9;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 3.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=UPF0506 protein SJCHGC02381;
DE   Flags: Precursor;
GN   ORFNames=SJCHGC02381;
OS   Schistosoma japonicum (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6182;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16617374; DOI=10.1371/journal.ppat.0020029;
RA   Liu F., Lu J., Hu W., Wang S.-Y., Cui S.-J., Chi M., Yan Q., Wang X.-R.,
RA   Song H.-D., Xu X.-N., Wang J.-J., Zhang X.-L., Zhang X., Wang Z.-Q.,
RA   Xue C.-L., Brindley P.J., McManus D.P., Yang P.-Y., Feng Z., Chen Z.,
RA   Han Z.-G.;
RT   "New perspectives on host-parasite interplay by comparative transcriptomic
RT   and proteomic analyses of Schistosoma japonicum.";
RL   PLoS Pathog. 2:268-281(2006).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0506 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAX24655.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AY808766; AAX24655.2; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q5C6R9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021712; UPF0506.
DR   Pfam; PF11703; UPF0506; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Knottin; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..150
FT                   /note="UPF0506 protein SJCHGC02381"
FT                   /id="PRO_0000311409"
FT   REGION          22..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        20
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        24
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        32
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        36
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        48
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        52
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        64
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        110
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        116..130
FT                   /evidence="ECO:0000305"
FT   DISULFID        123..134
FT                   /evidence="ECO:0000305"
FT   DISULFID        129..139
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   150 AA;  17383 MW;  8932695CA9DF3D5A CRC64;
     MNTCIQLLIL CLVTVINSEN STDNSTENTI KNETENATET ELPETFENET ENVSETELPE
     IIENETKIEA LNLPQIPKQK YCRTEGQYCS RTYFHRCCGN LVCQLHGFFN GTCVQCLAER
     KFCIWSSECC SKRCRLFRCR KNPYVQVIPY