ID   SKG1_ZYGRC              Reviewed;         334 AA.
AC   C5DSG3;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Suppressor of lethality of KEX2 GAS1 double null mutant protein 1;
GN   Name=SKG1; OrderedLocusNames=ZYRO0B16632g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Plays a role in cell wall integrity. Affects the cell wall
CC       polymer composition in the growing region of the cell (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III
CC       membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Bud
CC       membrane {ECO:0000250}; Single-pass type III membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Localizes on the
CC       inner surface of the plasma membrane at the bud and in the daughter
CC       cell. Localizes at an incipient bud site in the cells with emerging
CC       buds, a bud tip in small- or medium-budded cells, and a cell periphery
CC       in large-budded cells. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SKG1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928174; CAR26724.1; -; Genomic_DNA.
DR   RefSeq; XP_002495657.1; XM_002495612.1.
DR   AlphaFoldDB; C5DSG3; -.
DR   SMR; C5DSG3; -.
DR   STRING; 559307.C5DSG3; -.
DR   EnsemblFungi; CAR26724; CAR26724; ZYRO0B16632g.
DR   GeneID; 8202832; -.
DR   KEGG; zro:ZYRO0B16632g; -.
DR   HOGENOM; CLU_079389_0_0_1; -.
DR   InParanoid; C5DSG3; -.
DR   Proteomes; UP000008536; Chromosome B.
DR   GO; GO:0033101; C:cellular bud membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cell membrane; Cell wall biogenesis/degradation; Membrane;
KW   Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix.
FT   CHAIN           1..334
FT                   /note="Suppressor of lethality of KEX2 GAS1 double null
FT                   mutant protein 1"
FT                   /id="PRO_0000399677"
FT   TOPO_DOM        1..7
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical; Signal-anchor for type III membrane
FT                   protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..334
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          76..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..101
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   334 AA;  37761 MW;  6F4278AD9061CEC5 CRC64;
     MGDVSIAVGC AVGLPVGLSF LLAIVFWIRM QRRYKKEDAR DCELENIIRD ESGFISFDNL
     GTWQETQQEK KDVYVNDESV ESSGIQGSSS SEQLQQPNET HQNKHQSKHY MPAYRRNLNA
     YRIRQLPTGI NVDNNGSNLS LDSTQNMRKR PNLHQETVYD QMIPVLANTE PKLFSEDNNE
     QDTAATIQQN QQNNEKVIMK NLRNNDFGSY PRGTQSATSL SRSNSNSNTN TNTNVSRSSL
     HTRSSSVMSA VKGTTSYDNV FDTPKSATAA SLVDVKVSNN NNNNNKQPVY SLKNNYDIKN
     TSEIQEEDQY ENEFTNYSES KRTFIDSLRP KPGI