SKGA_CAUVC
ID SKGA_CAUVC Reviewed; 255 AA.
AC P0CAV4; Q9RP67;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=HTH-type transcriptional regulator SkgA;
DE AltName: Full=Stationary-phase regulation of KatG protein;
GN Name=skgA; OrderedLocusNames=CC_0694;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- FUNCTION: Regulates the induction of katG (catalase-peroxidase) in
CC stationary phase. {ECO:0000250}.
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DR EMBL; AE005673; AAK22679.1; -; Genomic_DNA.
DR PIR; C87335; C87335.
DR RefSeq; NP_419511.1; NC_002696.2.
DR RefSeq; WP_010918580.1; NC_002696.2.
DR PDB; 7CLA; X-ray; 2.50 A; A=1-255.
DR PDBsum; 7CLA; -.
DR AlphaFoldDB; P0CAV4; -.
DR SMR; P0CAV4; -.
DR STRING; 190650.CC_0694; -.
DR EnsemblBacteria; AAK22679; AAK22679; CC_0694.
DR KEGG; ccr:CC_0694; -.
DR PATRIC; fig|190650.5.peg.703; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_060077_0_6_5; -.
DR OMA; HAGHRRY; -.
DR BioCyc; CAULO:CC0694-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.10.490.50; -; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF46955; SSF46955; 1.
DR SUPFAM; SSF89082; SSF89082; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Activator; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..255
FT /note="HTH-type transcriptional regulator SkgA"
FT /id="PRO_0000098149"
FT DOMAIN 3..72
FT /note="HTH merR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
FT DNA_BIND 6..25
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
FT HELIX 6..13
FT /evidence="ECO:0007829|PDB:7CLA"
FT HELIX 17..25
FT /evidence="ECO:0007829|PDB:7CLA"
FT STRAND 40..42
FT /evidence="ECO:0007829|PDB:7CLA"
FT HELIX 44..58
FT /evidence="ECO:0007829|PDB:7CLA"
FT HELIX 63..71
FT /evidence="ECO:0007829|PDB:7CLA"
FT HELIX 77..109
FT /evidence="ECO:0007829|PDB:7CLA"
FT TURN 110..112
FT /evidence="ECO:0007829|PDB:7CLA"
FT HELIX 117..120
FT /evidence="ECO:0007829|PDB:7CLA"
FT HELIX 126..136
FT /evidence="ECO:0007829|PDB:7CLA"
SQ SEQUENCE 255 AA; 28965 MW; 020ABB9216549C5A CRC64;
MSVYTVKQMA RLSGVSVRAL HHYDAIGLLK PRAVGANGYR YYDRQDLLRL QQILFHRALE
TPLKDIQAAL DQPGFDLAAA LRAQRERLAA QAERYARLVD VVDRTLADLE GDETMDDKHL
FEGFDPEKQA RHEAWLVEHY GDEATRRIAD AKAGMKSWGK KDWSQFQEEA KAIEHDLAKA
LTQGLPVDSA PVTAIMRRHW AWVGRSWNRE PTPDAFAGLG HLYQANPEFT ARYEAIAPGL
TEYFSEAMRA FARGR
