ID   SKGR_XENLA              Reviewed;         213 AA.
AC   P13673;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 2.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Skin granule protein;
DE   Flags: Precursor;
GN   Name=sgp;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Skin;
RX   PubMed=2737290; DOI=10.1016/0014-5793(89)80644-1;
RA   Berger H., Keil G.;
RT   "The constituents of storage granules in the dermal glands of Xenopus
RT   laevis. Structure of a basic polypeptide deduced from cloned cDNA.";
RL   FEBS Lett. 249:293-296(1989).
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   EMBL; Y07507; CAA68806.1; -; mRNA.
DR   PIR; S04491; S04491.
DR   RefSeq; NP_001095215.1; NM_001101745.1.
DR   AlphaFoldDB; P13673; -.
DR   GeneID; 378604; -.
DR   KEGG; xla:378604; -.
DR   CTD; 378604; -.
DR   Xenbase; XB-GENE-6252402; sgp.S.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 378604; Expressed in zone of skin and 9 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..26
FT   CHAIN           27..213
FT                   /note="Skin granule protein"
FT                   /id="PRO_0000022349"
FT   REPEAT          27..48
FT                   /note="1"
FT   REPEAT          49..70
FT                   /note="2"
FT   REPEAT          71..92
FT                   /note="3"
FT   REPEAT          93..104
FT                   /note="4; truncated"
FT   REGION          27..104
FT                   /note="4 X 22 AA approximate tandem repeats"
FT   REGION          162..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..213
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   213 AA;  23361 MW;  903A5B987E212B49 CRC64;
     METMYHRFLC IPFLLILGLA QGQSKGLQTV TTFRTGLKPI DVTAIRTGLQ PIATFHTGQK
     PIDVTAIRTG LQPIATFHTG LQPVDVTAIR TGLQPIATFQ TGVQRVSTFH GEPASTLQGS
     GSTVIKKIMV SSMNQPVSKN EGIVEVPPPS GGTHVITEEM NWHGGRNGHK MKKLGKKKHH
     KNRHGGKNHH KMKKIGKHHG GGRKFGKKHR HHK