SKI14_ARATH
ID SKI14_ARATH Reviewed; 453 AA.
AC Q9LU91; Q8L720;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=F-box protein SKIP14;
DE AltName: Full=SKP1-interacting partner 14;
GN Name=SKIP14; OrderedLocusNames=At3g26000; ORFNames=MPE11.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP INTERACTION WITH CUL1; SKP1A/ASK1 AND SPK1B/ASK2.
RX PubMed=12795696; DOI=10.1046/j.1365-313x.2003.01768.x;
RA Risseeuw E.P., Daskalchuk T.E., Banks T.W., Liu E., Cotelesage J.,
RA Hellmann H., Estelle M., Somers D.E., Crosby W.L.;
RT "Protein interaction analysis of SCF ubiquitin E3 ligase subunits from
RT Arabidopsis.";
RL Plant J. 34:753-767(2003).
CC -!- FUNCTION: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase
CC complexes, which may mediate the ubiquitination and subsequent
CC proteasomal degradation of target proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBUNIT: Part of a SCF (ASK-cullin-F-box) protein ligase complex (By
CC similarity). Interacts with CUL1, SKP1A/ASK1 and SPK1B/ASK2.
CC {ECO:0000250, ECO:0000269|PubMed:12795696}.
CC -!- DOMAIN: The F-box is necessary for the interaction with ASK proteins.
CC {ECO:0000250}.
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DR EMBL; AB023041; BAB01063.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77100.1; -; Genomic_DNA.
DR EMBL; AY058077; AAL24185.1; -; mRNA.
DR EMBL; AY140009; AAM98151.1; -; mRNA.
DR EMBL; BT015945; AAV34775.1; -; mRNA.
DR RefSeq; NP_566787.1; NM_113504.3.
DR AlphaFoldDB; Q9LU91; -.
DR SMR; Q9LU91; -.
DR BioGRID; 7528; 7.
DR IntAct; Q9LU91; 8.
DR STRING; 3702.AT3G26000.1; -.
DR PaxDb; Q9LU91; -.
DR PRIDE; Q9LU91; -.
DR ProteomicsDB; 234539; -.
DR EnsemblPlants; AT3G26000.1; AT3G26000.1; AT3G26000.
DR GeneID; 822197; -.
DR Gramene; AT3G26000.1; AT3G26000.1; AT3G26000.
DR KEGG; ath:AT3G26000; -.
DR Araport; AT3G26000; -.
DR TAIR; locus:2092145; AT3G26000.
DR eggNOG; ENOG502QRGM; Eukaryota.
DR HOGENOM; CLU_034156_1_0_1; -.
DR InParanoid; Q9LU91; -.
DR OMA; ICQPLNE; -.
DR OrthoDB; 652726at2759; -.
DR PhylomeDB; Q9LU91; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9LU91; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LU91; baseline and differential.
DR Genevisible; Q9LU91; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0009788; P:negative regulation of abscisic acid-activated signaling pathway; IMP:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR SUPFAM; SSF81383; SSF81383; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..453
FT /note="F-box protein SKIP14"
FT /id="PRO_0000375237"
FT DOMAIN 34..104
FT /note="F-box; degenerate"
FT CONFLICT 402
FT /note="K -> E (in Ref. 3; AAM98151)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 453 AA; 50543 MW; CCD32A1DBA9039C4 CRC64;
MALNFSHRPF SSHLSEEPMM IANGNWCSSF DNGRKNTGGD ASSVDILDVL PSDPFGMDIN
NTFTAITGWL EDLEDDYNNQ YGRRRRDDIW IGDGNRQQLF AGLSFFWNNA MQFQSSGYSY
GSESLFGGAF DGSLFSTCKF PESSGENNGF GGALDGDGSC HGAFISASSV DEVLSHENAR
NGEVVGSSDR CNNGEEDAYV HPAIGFCLYH LRGKDLLSVS MVCKSLHTTV CDDTLLWKHI
HICRPLNEKI TEEALLHLTE RAQGTMQCLR IVDCCRITDD CLKRVVARNR QVVKIGVPGC
TRITIDGILS VLRDLKSAGK LQVKHLQLRG LFGVTKDHYD ELIDLLNIDN KVKQTIQKPR
FYHRGEACVS CDDDRALDIE MCPKCQNFKL VYDCPAEDCK GKKKGSEECR ACSLCIQRCY
HCGRCIIDTE YEEMFCLELL CAVCSKPTPK LTL
