SKI28_ARATH
ID SKI28_ARATH Reviewed; 292 AA.
AC Q9ZU90; Q8LGD0;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=F-box protein SKIP28;
DE AltName: Full=Protein MATERNAL EFFECT EMBRYO ARREST 11;
DE AltName: Full=SKP1-interacting partner 28;
GN Name=SKIP28; Synonyms=MEE11; OrderedLocusNames=At2g01620;
GN ORFNames=T8O11.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP INTERACTION WITH SKP1A/ASK1 AND CUL1.
RX PubMed=12795696; DOI=10.1046/j.1365-313x.2003.01768.x;
RA Risseeuw E.P., Daskalchuk T.E., Banks T.W., Liu E., Cotelesage J.,
RA Hellmann H., Estelle M., Somers D.E., Crosby W.L.;
RT "Protein interaction analysis of SCF ubiquitin E3 ligase subunits from
RT Arabidopsis.";
RL Plant J. 34:753-767(2003).
RN [7]
RP FUNCTION.
RX PubMed=15634699; DOI=10.1242/dev.01595;
RA Pagnussat G.C., Yu H.-J., Ngo Q.A., Rajani S., Mayalagu S., Johnson C.S.,
RA Capron A., Xie L.-F., Ye D., Sundaresan V.;
RT "Genetic and molecular identification of genes required for female
RT gametophyte development and function in Arabidopsis.";
RL Development 132:603-614(2005).
CC -!- FUNCTION: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase
CC complexes, which may mediate the ubiquitination and subsequent
CC proteasomal degradation of target proteins (By similarity). Required
CC during the endosperm development in embryos. {ECO:0000250,
CC ECO:0000269|PubMed:15634699}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBUNIT: Part of a SCF (ASK-cullin-F-box) protein ligase complex (By
CC similarity). Interacts with SKP1A/ASK1 and CUL1. {ECO:0000250,
CC ECO:0000269|PubMed:12795696}.
CC -!- INTERACTION:
CC Q9ZU90; P46639: KNAT1; NbExp=3; IntAct=EBI-604427, EBI-530486;
CC Q9ZU90; Q9FNV9: MYB113; NbExp=3; IntAct=EBI-604427, EBI-1546246;
CC Q9ZU90; Q39255: SKP1A; NbExp=3; IntAct=EBI-604427, EBI-532357;
CC -!- DOMAIN: The F-box is necessary for the interaction with ASK proteins.
CC {ECO:0000250}.
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DR EMBL; AC006069; AAD12709.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05474.1; -; Genomic_DNA.
DR EMBL; AK117653; BAC42307.1; -; mRNA.
DR EMBL; BT005175; AAO50708.1; -; mRNA.
DR EMBL; AY084339; AAM60922.1; -; mRNA.
DR PIR; A84427; A84427.
DR RefSeq; NP_565268.1; NM_126223.3.
DR AlphaFoldDB; Q9ZU90; -.
DR SMR; Q9ZU90; -.
DR BioGRID; 94; 9.
DR IntAct; Q9ZU90; 12.
DR STRING; 3702.AT2G01620.1; -.
DR PaxDb; Q9ZU90; -.
DR PRIDE; Q9ZU90; -.
DR ProteomicsDB; 232655; -.
DR EnsemblPlants; AT2G01620.1; AT2G01620.1; AT2G01620.
DR GeneID; 814691; -.
DR Gramene; AT2G01620.1; AT2G01620.1; AT2G01620.
DR KEGG; ath:AT2G01620; -.
DR Araport; AT2G01620; -.
DR TAIR; locus:2065418; AT2G01620.
DR eggNOG; ENOG502R97J; Eukaryota.
DR HOGENOM; CLU_076748_0_0_1; -.
DR InParanoid; Q9ZU90; -.
DR OMA; CIPRCEN; -.
DR OrthoDB; 1274556at2759; -.
DR PhylomeDB; Q9ZU90; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9ZU90; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZU90; baseline and differential.
DR Genevisible; Q9ZU90; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR032675; LRR_dom_sf.
PE 1: Evidence at protein level;
KW Developmental protein; Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..292
FT /note="F-box protein SKIP28"
FT /id="PRO_0000375240"
FT DOMAIN 21..79
FT /note="F-box; degenerate"
FT CONFLICT 75..76
FT /note="FS -> IT (in Ref. 5; AAM60922)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 292 AA; 33005 MW; 250E7397BF69569A CRC64;
MKTELEEEEE EEWRSVHEVL LIVLPYLHSL FELLSMIRVS RSLRDAIRDE TALWTKLVIE
PPLSSRLTDD ILSEFSSKSA GKLKTLILRQ CLMVTNKGLR RVVDANPLIT KIIVPGCSGL
TPEGIMECVE SLSKNNHKLE TLHINGVNGF TKQHLSALYT YLSSEGTIDL EVCPKCDEVR
MIPSCSRESC NQKQRKCRGC WLCIPRCAEC AVCLVGSDTE SQEAACGNDD VLCLECWLVL
PKCRFCNKPY CTNHSSRRHE IAITDAASRP SFECEACYYR AGTNPYEVDY QI
