SKIP3_ARATH
ID SKIP3_ARATH Reviewed; 294 AA.
AC Q9FV02; F4IQC4; Q9ZVQ7;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=F-box protein SKIP3;
DE AltName: Full=F-box protein PP2-B9;
DE AltName: Full=Protein PHLOEM PROTEIN 2-LIKE B9;
DE AltName: Full=SKP1-interacting partner 3;
GN Name=SKIP3; Synonyms=PP2B9; OrderedLocusNames=At2g02350;
GN ORFNames=T16F16.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 10-285, AND INTERACTION WITH SKP1A/ASK1.
RX PubMed=11387208; DOI=10.1093/emboj/20.11.2742;
RA Farras R., Ferrando A., Jasik J., Kleinow T., Oekresz L., Tiburcio A.,
RA Salchert K., del Pozo C., Schell J., Koncz C.;
RT "SKP1-SnRK protein kinase interactions mediate proteasomal binding of a
RT plant SCF ubiquitin ligase.";
RL EMBO J. 20:2742-2756(2001).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12529520; DOI=10.1104/pp.013086;
RA Dinant S., Clark A.M., Zhu Y., Vilaine F., Palauqui J.-C., Kusiak C.,
RA Thompson G.A.;
RT "Diversity of the superfamily of phloem lectins (phloem protein 2) in
RT angiosperms.";
RL Plant Physiol. 131:114-128(2003).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBUNIT: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By
CC similarity). Interacts with SKP1A/ASK1. {ECO:0000250,
CC ECO:0000269|PubMed:11387208}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC78517.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAG21978.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC005312; AAC78517.2; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; ANM61389.1; -; Genomic_DNA.
DR EMBL; AF263379; AAG21978.1; ALT_INIT; mRNA.
DR PIR; F84435; F84435.
DR RefSeq; NP_001318181.1; NM_001335105.1.
DR RefSeq; NP_565282.3; NM_126292.3.
DR AlphaFoldDB; Q9FV02; -.
DR BioGRID; 169; 1.
DR STRING; 3702.AT2G02350.1; -.
DR PaxDb; Q9FV02; -.
DR PRIDE; Q9FV02; -.
DR ProteomicsDB; 234569; -.
DR EnsemblPlants; AT2G02350.2; AT2G02350.2; AT2G02350.
DR GeneID; 814766; -.
DR Gramene; AT2G02350.2; AT2G02350.2; AT2G02350.
DR KEGG; ath:AT2G02350; -.
DR Araport; AT2G02350; -.
DR eggNOG; ENOG502QRA4; Eukaryota.
DR HOGENOM; CLU_050973_3_0_1; -.
DR InParanoid; Q9FV02; -.
DR OMA; LEYPSMI; -.
DR OrthoDB; 1051457at2759; -.
DR PhylomeDB; Q9FV02; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9FV02; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9FV02; baseline and differential.
DR Genevisible; Q9FV02; AT.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR025886; PP2-like.
DR Pfam; PF14299; PP2; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..294
FT /note="F-box protein SKIP3"
FT /id="PRO_0000272225"
FT DOMAIN 21..67
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ SEQUENCE 294 AA; 33354 MW; FDD6F37B3D12E127 CRC64;
MIRLRTLIEK NRSESRKKIV SSTLDSLPEG CISNIISFTS PEDACVAAAV SKIFESAVKS
DIVWEKFLPT DYESLITPSR VFSSKKELYF SLCNDPLLIE DGKMSLWLEK ASGKRCIMLS
ATAMNLSSMA DMSQRFLWIP CPESRFETVA ALREAYRFEF NCRMNTRVLS LRTRYSVYIV
FKKADNWCGF KGVSIEAVVG IVGEESFRSF ICFDTHGKGQ ARKRKVVAKP ELREDGWMET
EIGEFYNEGG LMSSDEVEIS TVEGKYAQQK RGLVILGIEI RPAKILEEFS VCRL