ID   SKL1_ARATH              Reviewed;         280 AA.
AC   Q9LW20;
DT   06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Probable inactive shikimate kinase like 1, chloroplastic;
DE            Short=AtSKL1;
DE   Flags: Precursor;
GN   Name=SKL1; OrderedLocusNames=At3g26900; ORFNames=MDJ14.24;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA   Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA   Shinozaki K.;
RT   "Analysis of multiple occurrences of alternative splicing events in
RT   Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL   DNA Res. 16:155-164(2009).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   FUNCTION, GENE FAMILY, NOMENCLATURE, AND DISRUPTION PHENOTYPE.
RX   PubMed=19057671; DOI=10.1371/journal.pgen.1000292;
RA   Fucile G., Falconer S., Christendat D.;
RT   "Evolutionary diversification of plant shikimate kinase gene duplicates.";
RL   PLoS Genet. 4:E1000292-E1000292(2008).
CC   -!- FUNCTION: Required for chloroplast biogenesis.
CC       {ECO:0000269|PubMed:19057671}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Albino plants. {ECO:0000269|PubMed:19057671}.
CC   -!- SIMILARITY: Belongs to the shikimate kinase family. {ECO:0000305}.
CC   -!- CAUTION: SKL1 does not possess shikimate kinase activity in vitro
CC       probably because it lacks the conserved active sites and substrate
CC       binding sites of the shikimate kinase family.
CC       {ECO:0000305|PubMed:19057671}.
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DR   EMBL; AB016889; BAB01237.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77235.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77236.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77237.1; -; Genomic_DNA.
DR   EMBL; AK318791; BAH56906.1; -; mRNA.
DR   EMBL; BT012132; AAS76227.1; -; mRNA.
DR   EMBL; BT012407; AAS92323.1; -; mRNA.
DR   RefSeq; NP_001118711.1; NM_001125239.1.
DR   RefSeq; NP_001118712.1; NM_001125240.1.
DR   RefSeq; NP_189325.2; NM_113602.4.
DR   AlphaFoldDB; Q9LW20; -.
DR   SMR; Q9LW20; -.
DR   BioGRID; 7636; 4.
DR   IntAct; Q9LW20; 4.
DR   STRING; 3702.AT3G26900.2; -.
DR   PaxDb; Q9LW20; -.
DR   PRIDE; Q9LW20; -.
DR   ProteomicsDB; 232659; -.
DR   EnsemblPlants; AT3G26900.1; AT3G26900.1; AT3G26900.
DR   EnsemblPlants; AT3G26900.2; AT3G26900.2; AT3G26900.
DR   EnsemblPlants; AT3G26900.3; AT3G26900.3; AT3G26900.
DR   GeneID; 822306; -.
DR   Gramene; AT3G26900.1; AT3G26900.1; AT3G26900.
DR   Gramene; AT3G26900.2; AT3G26900.2; AT3G26900.
DR   Gramene; AT3G26900.3; AT3G26900.3; AT3G26900.
DR   KEGG; ath:AT3G26900; -.
DR   Araport; AT3G26900; -.
DR   TAIR; locus:2088469; AT3G26900.
DR   eggNOG; ENOG502QSF9; Eukaryota.
DR   HOGENOM; CLU_057607_0_0_1; -.
DR   InParanoid; Q9LW20; -.
DR   OMA; ISIWVDV; -.
DR   OrthoDB; 1565621at2759; -.
DR   PhylomeDB; Q9LW20; -.
DR   PRO; PR:Q9LW20; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LW20; baseline and differential.
DR   Genevisible; Q9LW20; AT.
DR   GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR   GO; GO:0009570; C:chloroplast stroma; HDA:TAIR.
DR   GO; GO:0005829; C:cytosol; HDA:TAIR.
DR   GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR   GO; GO:0010027; P:thylakoid membrane organization; IMP:TAIR.
DR   CDD; cd00464; SK; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR031322; Shikimate/glucono_kinase.
DR   InterPro; IPR000623; Shikimate_kinase/TSH1.
DR   Pfam; PF01202; SKI; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Plastid; Reference proteome; Transit peptide.
FT   TRANSIT         1..54
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000305"
FT   CHAIN           55..280
FT                   /note="Probable inactive shikimate kinase like 1,
FT                   chloroplastic"
FT                   /id="PRO_0000421111"
SQ   SEQUENCE   280 AA;  30474 MW;  D6ED9087D0AA910A CRC64;
     MEIFSASASL TLTGFVPRLL PLLSPQARTT LCKPLLSSSS TRLISCHSRI APSRSLADQS
     ASTGISVVDS DPIDVVKRKA MDIAPELKGA SIFLVGINNS IKTNTGKLLA EALRYYYFDS
     DNLITEAAGG NVSAQALKEA DEKAFQESET EVLKQLSSMG RLVVCAGDGA VQSLRNLALL
     RHGISIWIDV PLDITAKGDD DSFHSEPSPE LFDTLKASYE KSRKGYETAD VSISLEKIAT
     KLEFEDLEAV TSEDIALEIL KEIEKLTRVK KMMEEASRPF