SKL2_ARATH
ID SKL2_ARATH Reviewed; 387 AA.
AC O82290; Q945M6;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Probable inactive shikimate kinase like 2, chloroplastic;
DE Short=AtSKL2;
DE Flags: Precursor;
GN Name=SKL2; OrderedLocusNames=At2g35500; ORFNames=T32F12.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19057671; DOI=10.1371/journal.pgen.1000292;
RA Fucile G., Falconer S., Christendat D.;
RT "Evolutionary diversification of plant shikimate kinase gene duplicates.";
RL PLoS Genet. 4:E1000292-E1000292(2008).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the shikimate kinase family. {ECO:0000305}.
CC -!- CAUTION: SKL2 does not possess shikimate kinase activity in vitro
CC probably because it lacks the conserved active sites and substrate
CC binding sites of the shikimate kinase family.
CC {ECO:0000305|PubMed:19057671}.
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DR EMBL; AC005314; AAC36171.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC09114.1; -; Genomic_DNA.
DR EMBL; AF412061; AAL06514.1; -; mRNA.
DR EMBL; AY074560; AAL67100.1; -; mRNA.
DR PIR; D84769; D84769.
DR RefSeq; NP_565805.1; NM_129102.4.
DR AlphaFoldDB; O82290; -.
DR SMR; O82290; -.
DR BioGRID; 3461; 8.
DR IntAct; O82290; 10.
DR STRING; 3702.AT2G35500.1; -.
DR PaxDb; O82290; -.
DR PRIDE; O82290; -.
DR ProteomicsDB; 232561; -.
DR EnsemblPlants; AT2G35500.1; AT2G35500.1; AT2G35500.
DR GeneID; 818115; -.
DR Gramene; AT2G35500.1; AT2G35500.1; AT2G35500.
DR KEGG; ath:AT2G35500; -.
DR Araport; AT2G35500; -.
DR TAIR; locus:2062486; AT2G35500.
DR eggNOG; ENOG502QS29; Eukaryota.
DR HOGENOM; CLU_050606_1_0_1; -.
DR InParanoid; O82290; -.
DR OMA; GWDPTHA; -.
DR OrthoDB; 1592635at2759; -.
DR PhylomeDB; O82290; -.
DR PRO; PR:O82290; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82290; baseline and differential.
DR Genevisible; O82290; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF49764; SSF49764; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..71
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 72..387
FT /note="Probable inactive shikimate kinase like 2,
FT chloroplastic"
FT /id="PRO_0000421112"
FT REGION 368..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 42687 MW; CF784D442E76503A CRC64;
MAAFASGLAI IFNSPSLNPV TTQATFLSSN RIRSSPRVFS GFHSLRRRGF RRFSQNVIPD
RFNSFSCNCL SAVSTSTIDY EFTDGGKEVE LRLRLKTGEI LSPKDISVDA DGTSLAVKEK
RNGLLITLLE TNHLFEKIMP SETIWYIDED QLVVNMKKVD GELKWPDIVE SWESLTAGMM
QLLKGASIYI VGDSTEINQK VSRELAVGLG YSPLDSKELL ESFSKQTIDS WILAEGPDSV
AEAESSVLES LSSHVRTVVS TLGGKHGAAG RADQWRHLYS GFTVWVSQTE ATDEESAKEE
ARRSKQEREI GYSNADVVVK LQGWDPTHAK SVAQASLSAL KQLIISDKGL PGKKSLYIRL
GCRGDWPNIK PPGWDPSSDT GPHPQFT
