SKP1_ORYSJ
ID SKP1_ORYSJ Reviewed; 173 AA.
AC Q6PL11; Q2R4Y1;
DT 20-DEC-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=SKP1-like protein 1 {ECO:0000303|PubMed:27436711};
DE AltName: Full=SKP1-like 1 {ECO:0000305};
GN Name=SKP1 {ECO:0000305}; Synonyms=OSK1 {ECO:0000303|PubMed:27436711};
GN OrderedLocusNames=Os11g0456300 {ECO:0000312|EMBL:BAT13929.1},
GN LOC_Os11g26910 {ECO:0000312|EMBL:ABA93508.1};
GN ORFNames=OsJ_33809 {ECO:0000312|EMBL:EAZ18273.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Zhao J., Zhang X.;
RT "Oryza sativa skp1 ortholog genes.";
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP INTERACTION WITH VIRUS P7-2 PROTEIN.
RX PubMed=24176102; DOI=10.1186/1743-422x-10-325;
RA Wang Q., Tao T., Han Y., Chen X., Fan Z., Li D., Yu J., Han C.;
RT "Nonstructural protein P7-2 encoded by Rice black-streaked dwarf virus
RT interacts with SKP1, a core subunit of SCF ubiquitin ligase.";
RL Virol. J. 10:325-325(2013).
RN [8]
RP INTERACTION WITH D3.
RX PubMed=24616269; DOI=10.1093/pcp/pcu045;
RA Zhao J., Wang T., Wang M., Liu Y., Yuan S., Gao Y., Yin L., Sun W.,
RA Peng L., Zhang W., Wan J., Li X.;
RT "DWARF3 participates in an SCF complex and associates with DWARF14 to
RT suppress rice shoot branching.";
RL Plant Cell Physiol. 55:1096-1109(2014).
RN [9]
RP INTERACTION WITH MOF, SUBCELLULAR LOCATION, AND DEVELOPMENTAL STAGE.
RX PubMed=27436711; DOI=10.1105/tpc.16.00108;
RA He Y., Wang C., Higgins J.D., Yu J., Zong J., Lu P., Zhang D., Liang W.;
RT "MEIOTIC F-BOX is essential for male meiotic DNA double-strand break repair
RT in rice.";
RL Plant Cell 28:1879-1893(2016).
RN [10]
RP INTERACTION WITH VIRUS P7-2 PROTEIN, AND IDENTIFICATION IN THE SCF COMPLEX.
RX PubMed=28494021; DOI=10.1371/journal.pone.0177518;
RA Tao T., Zhou C.J., Wang Q., Chen X.R., Sun Q., Zhao T.Y., Ye J.C., Wang Y.,
RA Zhang Z.Y., Zhang Y.L., Guo Z.J., Wang X.B., Li D.W., Yu J.L., Han C.G.;
RT "Rice black streaked dwarf virus P7-2 forms a SCF complex through binding
RT to Oryza sativa SKP1-like proteins, and interacts with GID2 involved in the
RT gibberellin pathway.";
RL PLoS ONE 12:E0177518-E0177518(2017).
CC -!- FUNCTION: Involved in ubiquitination and subsequent proteasomal
CC degradation of target proteins. Together with CUL1, a RING-box and a F-
CC box protein, it forms a SCF E3 ubiquitin ligase complex. The functional
CC specificity of this complex depends on the type of F-box protein. In
CC the SCF complex, it serves as an adapter that links the F-box protein
CC to CUL1. {ECO:0000250|UniProtKB:Q9FHW7}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000250|UniProtKB:Q9FHW7}.
CC -!- SUBUNIT: Part of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein
CC ligase complex (PubMed:28494021). Interacts directly with MOF (via F-
CC box domain) (PubMed:27436711). Interacts with rice black streaked dwarf
CC virus RBSDV protein P7-2 (PubMed:24176102, PubMed:28494021). Is able to
CC form the SCF complex together with CUL1 and the viral P7-2 protein
CC (PubMed:28494021). Interacts with D3 (PubMed:24616269).
CC {ECO:0000269|PubMed:24176102, ECO:0000269|PubMed:24616269,
CC ECO:0000269|PubMed:27436711, ECO:0000269|PubMed:28494021}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:27436711}.
CC -!- DEVELOPMENTAL STAGE: Highly expressed during early anther development.
CC {ECO:0000269|PubMed:27436711}.
CC -!- SIMILARITY: Belongs to the SKP1 family. {ECO:0000305}.
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DR EMBL; AY598357; AAT09201.1; -; mRNA.
DR EMBL; DP000010; ABA93508.1; -; Genomic_DNA.
DR EMBL; AP008217; BAH95253.1; -; Genomic_DNA.
DR EMBL; AP014967; BAT13929.1; -; Genomic_DNA.
DR EMBL; CM000148; EAZ18273.1; -; Genomic_DNA.
DR RefSeq; XP_015617535.1; XM_015762049.1.
DR AlphaFoldDB; Q6PL11; -.
DR SMR; Q6PL11; -.
DR STRING; 4530.OS11T0456300-01; -.
DR PaxDb; Q6PL11; -.
DR PRIDE; Q6PL11; -.
DR EnsemblPlants; Os11t0456300-01; Os11t0456300-01; Os11g0456300.
DR GeneID; 9270098; -.
DR Gramene; Os11t0456300-01; Os11t0456300-01; Os11g0456300.
DR KEGG; osa:9270098; -.
DR eggNOG; KOG1724; Eukaryota.
DR HOGENOM; CLU_059252_6_1_1; -.
DR OMA; PLKSADM; -.
DR OrthoDB; 1412723at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000007752; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR ExpressionAtlas; Q6PL11; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0009867; P:jasmonic acid mediated signaling pathway; IEA:UniProt.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR016897; SKP1.
DR InterPro; IPR001232; SKP1-like.
DR InterPro; IPR036296; SKP1-like_dim_sf.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR016072; Skp1_comp_dimer.
DR InterPro; IPR016073; Skp1_comp_POZ.
DR PANTHER; PTHR11165; PTHR11165; 1.
DR Pfam; PF01466; Skp1; 1.
DR Pfam; PF03931; Skp1_POZ; 1.
DR PIRSF; PIRSF028729; E3_ubiquit_lig_SCF_Skp; 1.
DR SMART; SM00512; Skp1; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR SUPFAM; SSF81382; SSF81382; 1.
PE 1: Evidence at protein level;
KW Host-virus interaction; Nucleus; Reference proteome;
KW Ubl conjugation pathway.
FT CHAIN 1..173
FT /note="SKP1-like protein 1"
FT /id="PRO_0000442778"
FT REGION 115..173
FT /note="Interaction with the F-box domain of F-box proteins"
FT /evidence="ECO:0000250|UniProtKB:Q39255"
FT CONFLICT 25
FT /note="A -> P (in Ref. 2; ABA93508 and 3; BAH95253)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 173 AA; 19042 MW; 6C6CEA06542BAD24 CRC64;
MAAEGEKKMI TLKSSDGEEF EVEEAVAMES QTIRHMIEDD CADNGIPLPN VNSKILSKVI
EYCNKHVHAA AAAASKAADD AASAAAAVPP PSGEDLKNWD ADFVKVDQAT LFDLILAANY
LNIKGLLDLT CQTVADMIKG KTPEEIRKTF NIKNDFTPEE EEEIRRENQW AFE
