SL1_BOTDP
ID SL1_BOTDP Reviewed; 32 AA.
AC C0HJQ0;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 04-FEB-2015, sequence version 1.
DT 25-MAY-2022, entry version 6.
DE RecName: Full=Snaclec {ECO:0000303|Ref.1};
DE Flags: Fragments;
OS Bothrops diporus (Chaco lancehead) (Bothrops neuwiedi diporus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Viperidae; Crotalinae; Bothrops.
OX NCBI_TaxID=1107943;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, SUBUNIT, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY.
RC TISSUE=Venom {ECO:0000303|Ref.1};
RA Yunes P.J., Madel N.P., Anal A.L., Rosario D., Fidelio G.D.;
RT "A constant area monolayer method to assess optimal lipid packing for
RT lipolysis tested with secreted phospholipases A2.";
RL Submitted (OCT-2014) to UniProtKB.
CC -!- FUNCTION: Interferes with one step of hemostasis (modulation of
CC platelet aggregation, or coagulation cascade, for example).
CC {ECO:0000305}.
CC -!- SUBUNIT: Dimer; disulfide-linked. {ECO:0000269|Ref.1}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
CC -!- MASS SPECTROMETRY: Mass=32460; Mass_error=30; Method=MALDI;
CC Evidence={ECO:0000269|Ref.1};
CC -!- SIMILARITY: Belongs to the snaclec family. {ECO:0000255}.
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DR AlphaFoldDB; C0HJQ0; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Hemostasis impairing toxin;
KW Platelet aggregation inhibiting toxin; Secreted; Toxin.
FT CHAIN 1..>32
FT /note="Snaclec"
FT /evidence="ECO:0000269|Ref.1"
FT /id="PRO_0000431696"
FT NON_CONS 8..9
FT /evidence="ECO:0000303|Ref.1"
FT NON_CONS 18..19
FT /evidence="ECO:0000303|Ref.1"
FT NON_TER 1
FT /evidence="ECO:0000303|Ref.1"
FT NON_TER 32
FT /evidence="ECO:0000303|Ref.1"
SQ SEQUENCE 32 AA; 3886 MW; 286CE758F0088F82 CRC64;
YYVWIGLRWV NIDCVEGNWS DYSSVSYENL VR