ID   BHLH9_RAT               Reviewed;         539 AA.
AC   Q71HP2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Protein BHLHb9;
DE            Short=bHLHb9;
DE   AltName: Full=Transcription regulator of 60 kDa;
DE            Short=p60TRP;
GN   Name=Bhlhb9;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15034937; DOI=10.1002/jcb.20010;
RA   Heese K., Yamada T., Akatsu H., Yamamoto T., Kosaka K., Nagai Y.,
RA   Sawada T.;
RT   "Characterizing the new transcription regulator protein p60TRP.";
RL   J. Cell. Biochem. 91:1030-1042(2004).
CC   -!- FUNCTION: May play a role in the control of cellular aging and
CC       survival. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Mainly cytoplasmic, and nuclear at lower level. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GPRASP family. {ECO:0000305}.
CC   -!- CAUTION: Despite its name, no basic helix-loop-helix (bHLH) domain is
CC       detected by any prediction tool. {ECO:0000305}.
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DR   EMBL; AF497483; AAQ07247.1; -; mRNA.
DR   RefSeq; NP_997494.1; NM_207611.1.
DR   RefSeq; XP_006257337.1; XM_006257275.3.
DR   RefSeq; XP_006257338.1; XM_006257276.2.
DR   RefSeq; XP_017457556.1; XM_017602067.1.
DR   RefSeq; XP_017457557.1; XM_017602068.1.
DR   AlphaFoldDB; Q71HP2; -.
DR   SMR; Q71HP2; -.
DR   STRING; 10116.ENSRNOP00000042638; -.
DR   PaxDb; Q71HP2; -.
DR   PRIDE; Q71HP2; -.
DR   Ensembl; ENSRNOT00000049375; ENSRNOP00000042638; ENSRNOG00000003191.
DR   Ensembl; ENSRNOT00000103691; ENSRNOP00000089209; ENSRNOG00000003191.
DR   Ensembl; ENSRNOT00000108351; ENSRNOP00000080161; ENSRNOG00000003191.
DR   Ensembl; ENSRNOT00000110806; ENSRNOP00000089980; ENSRNOG00000003191.
DR   GeneID; 317407; -.
DR   KEGG; rno:317407; -.
DR   UCSC; RGD:1303224; rat.
DR   CTD; 80823; -.
DR   RGD; 1303224; Bhlhb9.
DR   eggNOG; ENOG502RU0K; Eukaryota.
DR   GeneTree; ENSGT00940000161990; -.
DR   HOGENOM; CLU_036908_0_0_1; -.
DR   InParanoid; Q71HP2; -.
DR   OMA; PIPEYPF; -.
DR   PhylomeDB; Q71HP2; -.
DR   PRO; PR:Q71HP2; -.
DR   Proteomes; UP000002494; Chromosome X.
DR   Bgee; ENSRNOG00000003191; Expressed in cerebellum and 19 other tissues.
DR   Genevisible; Q71HP2; RN.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0042803; F:protein homodimerization activity; ISO:RGD.
DR   GO; GO:0007611; P:learning or memory; ISO:RGD.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISO:RGD.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISO:RGD.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISO:RGD.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISO:RGD.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR006911; ARM-rpt_dom.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR043374; BHLHb9/GASP-1/GASP-2.
DR   PANTHER; PTHR46414; PTHR46414; 1.
DR   Pfam; PF04826; Arm_2; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..539
FT                   /note="Protein BHLHb9"
FT                   /id="PRO_0000334665"
FT   REGION          1..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          132..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..52
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..150
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  59718 MW;  991568BB794B2677 CRC64;
     MTGSKNKARA QAKLEKRASA QAKAAAEREA ANAGRGAGKN RDKGKGKAGS KTDAVAEAKA
     GSKSKVVAET KEGARPESKA VAKGTSDFNH KAENKYARSA RKDKPSSDSW FWAGEDSGIN
     SWFWKGEEVS NNSVAKCENK PSTSIQARVE EHTPRTSHKS RSGAEEEEEE NVIGNWFWEG
     DDTGFDSDPK PVFKIVKPQP VDEINEKDRP KDWSEVTIWP KAPAVTPAVL GYRSQDSSEG
     RPSSYIVLAS NEEETSTTCT KNTRSSLQPI PEYPFGSDPC IQTLDEIRQQ IKIREENGIK
     PFACPCKMEC YLDSPEFEKL VNILKSTTDP LIHKIAQIAM GIHKVHPFAQ EFINEVGVVT
     LIESLLSFSS PEVSIKKAVI TLNSSGDDRQ QMVEFHVKHM CKETVSFPLN SPGQQSGLKI
     IGQLTTESVH HYIVVSYFSE LFHLLSQGNR KTRNLVLKVF LNMSENPKAA RDMINMKALA
     ALKLIFNQKE AKANLVSAVA IFINIKEHIR KGSIVVVDHL SYNTLTAIFR EVKGIIERM