SL9P1_HUMAN
ID SL9P1_HUMAN Reviewed; 282 AA.
AC A6NJY1;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2012, sequence version 4.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Putative SLC9B1-like protein SLC9B1P1;
DE AltName: Full=Solute carrier family 9 subfamily B member 1 pseudogene 1;
GN Name=SLC9B1P1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12815422; DOI=10.1038/nature01722;
RA Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W.,
RA Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A.,
RA Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R.,
RA Graves T.A., Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R.,
RA McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S.,
RA Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P.,
RA Waterston R.H., Wilson R.K., Rozen S., Page D.C.;
RT "The male-specific region of the human Y chromosome is a mosaic of discrete
RT sequence classes.";
RL Nature 423:825-837(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 1 (CPA1)
CC transporter (TC 2.A.36) family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC134882; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A6NJY1; -.
DR SMR; A6NJY1; -.
DR BioMuta; HGNC:37492; -.
DR MassIVE; A6NJY1; -.
DR PaxDb; A6NJY1; -.
DR PeptideAtlas; A6NJY1; -.
DR PRIDE; A6NJY1; -.
DR GeneCards; SLC9B1P1; -.
DR HGNC; HGNC:37492; SLC9B1P1.
DR neXtProt; NX_A6NJY1; -.
DR InParanoid; A6NJY1; -.
DR ChiTaRS; SLC9B1P1; human.
DR Pharos; A6NJY1; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; A6NJY1; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR030187; SLC9B1.
DR PANTHER; PTHR31102:SF5; PTHR31102:SF5; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 5: Uncertain;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..282
FT /note="Putative SLC9B1-like protein SLC9B1P1"
FT /id="PRO_0000341232"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 282 AA; 30828 MW; 1CB1764A4ED36C77 CRC64;
MVLQENGYGV EEDIPTLLMA ASSMDDLLAI TGFNTCLSIV FYSGGMINNA IASLRNVCIS
LLAGIVLGFF VRYFPSEDQK KITLKRGFLV LITFVSAVLG SQPIGLHGSG GLCTLVLHFI
EWTKWSQEKM KVQKIITNVW DIFQPLLFGL VGAEVSVSLL ESNIVGISVS TLSLALCVRI
LNIYLLMCFA GFSFKEKIFI ALAWMPKATV QAVLGPLALE TARVSTPHLE TYAKDVMTVA
FLAIMITAPN GALLMGILGP KMLTRHYDPS KIKLQLSTLE HH