ID   SLAB_METS5              Reviewed;         416 AA.
AC   A4YHQ9;
DT   23-MAY-2018, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=S-layer protein B {ECO:0000303|PubMed:19522740};
DE   AltName: Full=Surface layer small protein {ECO:0000305};
DE   Flags: Precursor;
GN   Name=slaB {ECO:0000303|PubMed:19522740};
GN   OrderedLocusNames=Msed_1807 {ECO:0000312|EMBL:ABP95961.1};
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2;
RX   PubMed=18083856; DOI=10.1128/aem.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
RN   [2]
RP   FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
RX   PubMed=19522740; DOI=10.1111/j.1365-2958.2009.06746.x;
RA   Veith A., Klingl A., Zolghadr B., Lauber K., Mentele R., Lottspeich F.,
RA   Rachel R., Albers S.V., Kletzin A.;
RT   "Acidianus, Sulfolobus and Metallosphaera surface layers: structure,
RT   composition and gene expression.";
RL   Mol. Microbiol. 73:58-72(2009).
CC   -!- FUNCTION: S-layer small protein. May anchor the complex to the cell
CC       membrane. {ECO:0000269|PubMed:19522740}.
CC   -!- SUBUNIT: The mushroom-shaped unit cells of the Sulfolobales' S-layers
CC       may consist of three SlaB subunits and six SlaA subunits.
CC       {ECO:0000305|PubMed:19522740}.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer
CC       {ECO:0000305|PubMed:19522740}. Cell membrane {ECO:0000255}; Single-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the Sulfolobales SlaB family. {ECO:0000305}.
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DR   EMBL; CP000682; ABP95961.1; -; Genomic_DNA.
DR   RefSeq; WP_012021748.1; NC_009440.1.
DR   AlphaFoldDB; A4YHQ9; -.
DR   STRING; 399549.Msed_1807; -.
DR   EnsemblBacteria; ABP95961; ABP95961; Msed_1807.
DR   GeneID; 5105370; -.
DR   GeneID; 59457068; -.
DR   KEGG; mse:Msed_1807; -.
DR   eggNOG; arCOG02981; Archaea.
DR   HOGENOM; CLU_670155_0_0_2; -.
DR   OMA; YENTYPQ; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   InterPro; IPR013784; Carb-bd-like_fold.
DR   SUPFAM; SSF49452; SSF49452; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Cell wall; Coiled coil; Membrane; Reference proteome;
KW   S-layer; Secreted; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..416
FT                   /note="S-layer protein B"
FT                   /id="PRO_0000444054"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          310..330
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   416 AA;  43427 MW;  3CA42E159A4CF81B CRC64;
     MKYNLLPLIL LSLLVAPLLA MGSAPAITVT TQPVYHPGQT VFISGVTSPN TLVGITIYNP
     QGKAVYSNTT TSGPNGDYSL KAFTFPLQES TTFPFGTYTV QVGTQTGFTN STTFQFLPLT
     ATVNVLVVNP QGVPIQGATV TADSVTATTN ASGQAVLNLP TGTYTLKVVP PSPYSPASEN
     ITVTAPNTYS FKITVQIQEL ALQVVSATSP NVNLKDLTSG TSITMIGGTT LTLMSMVTFA
     GQPISTATVT AMYNGTMYNA TYMNGYYVIT ISVPNTQYET DLVIQATYSG MQSNTVTLPL
     TVNVNEQAII ASLNSTIQSL ESQISSLSST VSTLSSSVTS LSNTVSSLSS TVSKLNGTVA
     SLQSSVSTLS SEYSTLNSRV NALSGLSGTV DIALAVSIIA IIISIVVLIL VFRKIS