ID   SLAB_SACS2              Reviewed;         397 AA.
AC   Q980C6;
DT   23-MAY-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=S-layer protein B {ECO:0000303|PubMed:19522740};
DE   AltName: Full=Surface layer small protein {ECO:0000305};
DE   Flags: Precursor;
GN   Name=slaB {ECO:0000303|PubMed:19522740};
GN   OrderedLocusNames=SSO0390 {ECO:0000312|EMBL:AAK40717.1};
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
RN   [2]
RP   PROTEIN SEQUENCE OF 25-31, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION,
RP   INDUCTION, AND DOMAIN.
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=19522740; DOI=10.1111/j.1365-2958.2009.06746.x;
RA   Veith A., Klingl A., Zolghadr B., Lauber K., Mentele R., Lottspeich F.,
RA   Rachel R., Albers S.V., Kletzin A.;
RT   "Acidianus, Sulfolobus and Metallosphaera surface layers: structure,
RT   composition and gene expression.";
RL   Mol. Microbiol. 73:58-72(2009).
CC   -!- FUNCTION: S-layer small protein. May anchor the complex to the cell
CC       membrane. {ECO:0000269|PubMed:19522740}.
CC   -!- SUBUNIT: The mushroom-shaped unit cells of the Sulfolobales' S-layers
CC       may consist of three SlaB subunits and six SlaA subunits.
CC       {ECO:0000305|PubMed:19522740}.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer
CC       {ECO:0000305|PubMed:19522740}. Cell membrane {ECO:0000255}; Single-pass
CC       membrane protein {ECO:0000255}.
CC   -!- INDUCTION: Constitutively expressed. {ECO:0000269|PubMed:19522740}.
CC   -!- DOMAIN: Composed of consecutive beta sandwich domains, a coiled-coil
CC       domain and a C-terminal transmembrane helix.
CC       {ECO:0000269|PubMed:19522740}.
CC   -!- SIMILARITY: Belongs to the Sulfolobales SlaB family. {ECO:0000305}.
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DR   EMBL; AE006641; AAK40717.1; -; Genomic_DNA.
DR   PIR; F90182; F90182.
DR   RefSeq; WP_010922961.1; NC_002754.1.
DR   AlphaFoldDB; Q980C6; -.
DR   SMR; Q980C6; -.
DR   STRING; 273057.SSO0390; -.
DR   EnsemblBacteria; AAK40717; AAK40717; SSO0390.
DR   GeneID; 44129367; -.
DR   KEGG; sso:SSO0390; -.
DR   PATRIC; fig|273057.12.peg.384; -.
DR   eggNOG; arCOG07272; Archaea.
DR   HOGENOM; CLU_697598_0_0_2; -.
DR   OMA; YENTYPQ; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Cell membrane; Cell wall; Coiled coil; Direct protein sequencing; Membrane;
KW   Reference proteome; S-layer; Secreted; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000269|PubMed:19522740"
FT   CHAIN           25..397
FT                   /note="S-layer protein B"
FT                   /id="PRO_0000444055"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          259..314
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   397 AA;  41546 MW;  01C2618BA0D7C2DA CRC64;
     MVVKKTFVLS TLILISVVAL VSTAVYTSGN VTFYSPSVNN QIYYVGKSVT IDAVVPQQFA
     GQGAVINLFF PNSTLAASIP TTVNATGGIY VPNAYTFPHV IGIWQITVEV TGGVAVGTID
     VNVTTPAVAP IILTLQNLAM YENTYPQFIE FANGIITSVV MQNGTVNIMG YVYNSTVGPL
     SGATVSLTLN IPTVGTKTLS TTTASNGSFM LSFQVPQLST TLTLISSYLI SGSLTVSYGV
     HTVTYNVFIT AIPNYLSVIN ALNNEVSTLR SEISSLNSTI ASLNKSLANA NTQISNLQSE
     ITTLNSEIGK LNSTVGSLST QLSSLSSQYN TLSSQVTALN GKISNLSTSL STLNGEVASL
     RSTVSSLTTI AYGGIIAGII GLIVAIVAIV LVMRRIS