ID   SLAPH_BRECH             Reviewed;        1116 AA.
AC   P38538;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Surface layer protein;
DE   AltName: Full=Hexagonal wall protein;
DE            Short=HWP;
DE   Flags: Precursor;
OS   Brevibacillus choshinensis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=54911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 54-68.
RC   STRAIN=HPD31;
RX   PubMed=2307650; DOI=10.1128/jb.172.3.1312-1320.1990;
RA   Ebisu S., Tsuboi A., Takagi H., Naruse Y., Yamagata H., Tsukagoshi N.,
RA   Udaka S.;
RT   "Conserved structures of cell wall protein genes among protein-producing
RT   Bacillus brevis strains.";
RL   J. Bacteriol. 172:1312-1320(1990).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer. Note=This bacterium
CC       is covered by a S-layer with hexagonal symmetry.
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DR   EMBL; D90050; BAA14103.1; -; Genomic_DNA.
DR   AlphaFoldDB; P38538; -.
DR   SMR; P38538; -.
DR   PRIDE; P38538; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR   InterPro; IPR001119; SLH_dom.
DR   Pfam; PF00395; SLH; 2.
DR   PROSITE; PS51272; SLH; 2.
PE   1: Evidence at protein level;
KW   Cell wall; Direct protein sequencing; Repeat; S-layer; Secreted; Signal.
FT   SIGNAL          1..53
FT                   /evidence="ECO:0000269|PubMed:2307650"
FT   CHAIN           54..1116
FT                   /note="Surface layer protein"
FT                   /id="PRO_0000032644"
FT   DOMAIN          54..117
FT                   /note="SLH 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00777"
FT   DOMAIN          118..181
FT                   /note="SLH 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00777"
FT   DOMAIN          182..231
FT                   /note="SLH 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00777"
SQ   SEQUENCE   1116 AA;  123397 MW;  86D583D7AC72546F CRC64;
     MQDSGFKKKD RSTNIPQEQF VYTRGGEHKV MKKVVNSVLA SALAITVAPM AFAAEDTTTA
     PKMDAAMEKT VKRLEALGLV AGYGNGDFGA DKTITRAEFA TLIVRARGLE QGAKLAQFNT
     TYTDVRSTDW FAGFVNVASG EEIVKGFPDK SFKPQNQVTY AEAVTMIVRA LGYEPSVRGV
     WPNSMISKGS ELNIAKGINN PNMQQFAATI FKMLDNALRV KLMEQIEYGT DIRLNVTDET
     LLTKYLKVTV RDMDWAHEKG NNSDELPLVT NVPAIGLGSL KANEVTLNGK DADLGSNTTY
     KVAEGINPNA FDGQKVQVWI KDDRENVIVW MEGSEDEDVV MDRVSALYLK GKAFTDDIVK
     DLSKSDLDDV KIEMDGSEKS YRLTEDTKIT YNFTRFNDPV DALSKIYKDN DTFGVKVVLN
     DNNEVAYLHI IDDQTIDKSV KGVKYGSKVI SKIDADKKKI TNLDNSKFSD LEDQDEGKDF
     LVFLDGQPAK LGDLKESDVY SVYYADGDKD KYLVFANRNV AEGKVEKVVS RNKTDIRLTV
     GGKTYKVYPD ASYSENANKD VKKVNSDLDL ISNLDGEEVK LLLDPSGRVR HIETKDAIDD
     RKPLAIITKG ATYNSSKDTY DFTVMTQKGK TQIVSLDQKD IYDRYGVNYD KSNDKRQAFE
     KDLVELLQPK VVKEDSATDA NQTVLLEVNF DSKGEVDKVK VLDSKLKYSE KSTWDKLADE
     DDDVVGDYEV TDKTAVFKMT GDLTPATGTK RGELKNAGTA KFKDVAKKSD LKVWYSVDED
     KGEVQAIFVV DGSGLGGDHQ FGMVKQYGTA SKQDTITIVT KDGDSVTEKE YKLDGDADDL
     KVDQDIRRGD VISFTLNSDG EVIVDDVVEV VNNNHIDNTA SKSATLMPED ERQKAGIDKL
     VVARVDEVDG NTISLNYADG KTQKYYTKAS TAFIDVYDGL EGIDGVDEGD YIVMIDSADI
     DGTRFDYVLV VSSDDEIRTQ HISTKAVTDF LNKPTRLCTK SWRWGRSSHG TKVNTVNDEA
     VVDGIVTLPA DASVRNFNIA FDQEINSKDA TVTVTNEDTL GNVTVSEVAT DAKVLSFKTA
     KLDTTKTYII TVKGLKDKNG KAVKDVTLYV EFVAGV