ID   SLAP_CAMFE              Reviewed;         939 AA.
AC   P35827; Q841X5;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   15-AUG-2003, sequence version 2.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=S-layer protein;
DE   AltName: Full=Surface array protein;
DE            Short=SAP;
GN   Name=sapA;
OS   Campylobacter fetus.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-20.
RC   STRAIN=84-32 / 23D;
RX   PubMed=2387868; DOI=10.1016/s0021-9258(18)77335-3;
RA   Blaser M.J., Gotschlich E.C.;
RT   "Surface array protein of Campylobacter fetus. Cloning and gene
RT   structure.";
RL   J. Biol. Chem. 265:14529-14535(1990).
RN   [2]
RP   ERRATUM OF PUBMED:2387868.
RX   PubMed=2229082; DOI=10.1016/s0021-9258(17)30670-1;
RA   Blaser M.J., Gotschlich E.C.;
RL   J. Biol. Chem. 265:19372-19372(1990).
RN   [3]
RP   SEQUENCE REVISION.
RA   Tu Z.-C., Wassenaar T.M., Thompson S.A., Blaser M.J.;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The S-layer is a paracrystalline mono-layered assembly of
CC       proteins which coats the surface of bacteria. This protein is critical
CC       for virulence.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer. Note=This bacterium
CC       is covered by a S-layer with hexagonal symmetry.
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DR   EMBL; AY211269; AAO64227.1; -; Genomic_DNA.
DR   PIR; A37284; A37284.
DR   AlphaFoldDB; P35827; -.
DR   SMR; P35827; -.
DR   STRING; 983328.AFGH01000010_gene943; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Calcium; Cell wall; Direct protein sequencing; S-layer; Secreted;
KW   Virulence.
FT   CHAIN           1..939
FT                   /note="S-layer protein"
FT                   /id="PRO_0000205335"
SQ   SEQUENCE   939 AA;  95508 MW;  AB532B4FDAC571D9 CRC64;
     MLNKTDVSML YITIMGMASE GDGNKYWLDY ANNNSLGVSS LANIMLDSPG AAKFFGDSLL
     AGNEKDFVTK IYSIALGNTS DVDGINYWTK AITGGGEFTD SKGNVISVAS LSKGDLIGAM
     INSMVNGGSA ESKAIFEAKA AASDYFADAT LVRDISGLDE GTTSKLISEI NSASDLDKVK
     SEIDALKSEL PNPGSTYDLT EGNDNLKGTD LDDTFNGTTY VGNGTNKSTL SAFDKIDGGA
     GRDTLNAIFT ANNNAAAATK LDQAEIDKSL KGVTNVENIN IISDLETSGD FVFNGYEKVG
     FNVLGDIVSF ATDASKSVNV ETTGTITAFT AAGTGKVDVV AGKISALTAD SATSVNLTAT
     NDTITLTSAN AATSVNLKTS GAAKSATITS ANAAKNITID ATGVAAVTSA TAVENLTVKH
     ATNVTLAGNM DKLATVTLDN AALTAAIDIK SASTLNLINS SVNGHNISTA AKDVTVNLSG
     SAAKVKLNTT AATDQTVTLK ANATDNSLEF DSATAKTTSV TASGSGKTLV IKGAEVETLV
     NIDTTAFNGA ADVSFGKDGQ GGKFSVKTGT GDDKIEFVGT TLTEGSVIDG AGNDTIAMKS
     AALTSANFTM IKNIENVAIS DAVATADLSS SAFKNSVIIT TKEAADTTLT INKDQVINFT
     AADAGSVKLI TVKLNDVTGA NDVVKIVLDA AAKDASIALG TAAADKALVI DTGIETLNIT
     SLVKATSPET TANTVNAKLT DVTSIIIDGD AKITLGHAGT AGTDYSKVSM IDASALKAGL
     TFDASAITLG ANATIKGGSG ADSITVKGGN IVVDLVAGGD DTITLKKGAE KTDITTVNNF
     NAGDKIDIAD AKNGTFTFNK ITMNSDANLD DYITKAVAGD GSTNSAVSYF LHNGYTYVVV
     DGTAGATFTK ATDTIIKLSG TLDLKLSGDN VVVDDGSVI