ID   SLAP_GEOSE              Reviewed;        1228 AA.
AC   P35825;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=S-layer protein;
DE   AltName: Full=Surface layer protein;
DE   Flags: Precursor;
GN   Name=sbsA;
OS   Geobacillus stearothermophilus (Bacillus stearothermophilus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=1422;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PV72;
RX   PubMed=8045409; DOI=10.1016/0378-1119(94)90332-8;
RA   Kuen B., Sleytr U.B., Lubitz W.;
RT   "Sequence analysis of the sbsA gene encoding the 130-kDa surface-layer
RT   protein of Bacillus stearothermophilus strain PV72.";
RL   Gene 145:115-120(1994).
CC   -!- FUNCTION: The S-layer is a paracrystalline mono-layered assembly of
CC       proteins which coat the surface of bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer. Note=This bacterium
CC       is covered by a S-layer with hexagonal symmetry.
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DR   EMBL; X71092; CAA50409.1; -; Genomic_DNA.
DR   EMBL; AX000218; CAB77069.1; -; Unassigned_DNA.
DR   PIR; I40468; I40468.
DR   AlphaFoldDB; P35825; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.1220; -; 5.
DR   InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR   InterPro; IPR041378; S-layer_SbsC_C.
DR   InterPro; IPR032812; SbsA_Ig.
DR   Pfam; PF13205; Big_5; 5.
DR   Pfam; PF18058; SbsC_C; 1.
PE   3: Inferred from homology;
KW   Cell wall; S-layer; Secreted; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..1228
FT                   /note="S-layer protein"
FT                   /id="PRO_0000032632"
SQ   SEQUENCE   1228 AA;  131076 MW;  9F1383AD810C0B0F CRC64;
     MDRKKAVKLA TASAIAASAF VAANPNASEA ATDVATVVSQ AKAQFKKAYY TYSHTVTETG
     EFPNINDVYA EYNKAKKRYR DAVALVNKAG GAKKDAYLAD LQKEYETYVF KANPKSGEAR
     VATYIDAYNY ATKLDEMRQE LEAAVQAKDL EKAEQYYHKI PYEIKTRTVI LDRVYGKTTR
     DLLRSTFKAK AQELRDSLIY DITVAMKARE VQDAVKAGNL DKAKAAVDQI NQYLPKVTDA
     FKTELTEVAK KALDADEAAL TPKVESVSAI NTQNKAVELT AVPVNGTLKL QLSAAANEDT
     VNVNTVRIYK VDGNIPFALN TADVSLSTDG KTITVDASTP FENNTEYKVV VKGIKDKNGK
     EFKEDAFTFK LRNDAVVTQV FGTNVTNNTS VNLAAGTFDT DDTLTVVFDK LLAPETVNSS
     NVTITDVETG KRIPVIASTS GSTITITLKE ALVTGKQYKL AINNVKTLTG YNAEAYELVF
     TANASAPTVA TAPTTLGGTT LSTGSLTTNV WGKLAGGVNE AGTYYPGLQF TTTFATKLDE
     STLADNFVLV EKESGTVVAS ELKYNADAKM VTLVPKADLK ENTIYQIKIK KGLKSDKGIE
     LGTVNEKTYE FKTQDLTAPT VISVTSKNGD AGLKVTEAQE FTVKFSENLN TFNATTVSGS
     TITYGQVAVV KAGANLSALT ASDIIPASVE AVTGQDGTYK VKVAANQLER NQGYKLVVFG
     KGATAPVKDA ANANTLATNY IYTFTTEGQD VTAPTVTKVF KGDSLKDADA VTTLTNVDAG
     QKFTIQFSEE LKTSSGSLVG GKVTVEKLTN NGWVDAGTGT TVSVAPKTDA NGKVTAAVVT
     LTGLDNNDKD AKLRLVVDKS STDGIADVAG NVIKEKDILI RYNSWRHTVA SVKAAADKDG
     QNASAAFPTS TAIDTTKSLL VEFNETDLAE VKPENIVVKD AAGNAVAGTV TALDGSTNKF
     VFTPSQELKA GTVYSVTIDG VRDKVGNTIS KYITSFKTVS ANPTLSSISI ADGAVNVDRS
     KTITIEFSDS VPNPTITLKK ADGTSFTNYT LVNVNNENKT YKIVFHKGVT LDEFTQYELA
     VSKDFQTGTD IDSKVTFITG SVATDEVKPA LVGVGSWNGT SYTQDAAATR LRSVADFVAE
     PVALQFSEGI DLTNATVTVT NITDDKTVEV ISKESVDADH DAGATKETLV INTVTPLVLD
     NSKTYKIVVS GVKDAAGNVA DTITFYIK