SLC2_ORYSJ
ID SLC2_ORYSJ Reviewed; 378 AA.
AC Q651B6; A0A0P0XRV8; Q0IZG2;
DT 22-APR-2020, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Probable 2-oxoglutarate-dependent dioxygenase SLC2 {ECO:0000305};
DE EC=1.14.11.- {ECO:0000255|PROSITE-ProRule:PRU00805};
DE AltName: Full=Protein SLENDER AND CRINKLY LEAF 2 {ECO:0000303|PubMed:31701152};
GN Name=SLC2 {ECO:0000303|PubMed:31701152};
GN OrderedLocusNames=Os09g0570800 {ECO:0000312|EMBL:BAT09516.1},
GN LOC_Os09g39720 {ECO:0000305};
GN ORFNames=B1331F11.1 {ECO:0000312|EMBL:BAD46601.1},
GN OsJ_30422 {ECO:0000312|EMBL:EAZ45741.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=31701152; DOI=10.1093/jxb/erz501;
RA Liu X., Cai W.J., Yin X., Yang D., Dong T., Feng Y.Q., Wu Y.;
RT "Two dioxygenases, SLC1 and SLC2, play essential roles in shoot development
RT of rice.";
RL J. Exp. Bot. 71:1387-1401(2020).
CC -!- FUNCTION: Involved in the regulation of shoot development and salicylic
CC acid (SA) homeostasis. {ECO:0000269|PubMed:31701152}.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000255|PROSITE-ProRule:PRU00805};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000255|PROSITE-
CC ProRule:PRU00805};
CC -!- COFACTOR:
CC Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
CC Evidence={ECO:0000250|UniProtKB:D4N500};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:31701152}. Nucleus
CC {ECO:0000269|PubMed:31701152}.
CC -!- TISSUE SPECIFICITY: Expressed in coleoptiles, leaf sheaths, leaf blades
CC and root tips of young seedlings (PubMed:31701152). Expressed in
CC vascular bundles of mature leaf blades (PubMed:31701152). Expressed in
CC developing culms and nodes (PubMed:31701152).
CC {ECO:0000269|PubMed:31701152}.
CC -!- MISCELLANEOUS: Plants overexpressing SLC1 are infertile and exhibit
CC defects in shoot development characterized by slender and crinkly
CC leaves. {ECO:0000269|PubMed:31701152}.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF25903.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAT09516.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AP006162; BAD46601.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25903.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP014965; BAT09516.1; ALT_INIT; Genomic_DNA.
DR EMBL; CM000146; EAZ45741.1; -; Genomic_DNA.
DR RefSeq; XP_015612585.1; XM_015757099.1.
DR AlphaFoldDB; Q651B6; -.
DR SMR; Q651B6; -.
DR STRING; 4530.OS09T0570800-01; -.
DR EnsemblPlants; Os09t0570800-01; Os09t0570800-01; Os09g0570800.
DR GeneID; 4347916; -.
DR Gramene; Os09t0570800-01; Os09t0570800-01; Os09g0570800.
DR KEGG; osa:4347916; -.
DR eggNOG; KOG0143; Eukaryota.
DR HOGENOM; CLU_010119_16_4_1; -.
DR InParanoid; Q651B6; -.
DR OrthoDB; 1005149at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.330; -; 1.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Developmental protein; Dioxygenase; Iron; Metal-binding;
KW Nucleus; Oxidoreductase; Reference proteome.
FT CHAIN 1..378
FT /note="Probable 2-oxoglutarate-dependent dioxygenase SLC2"
FT /id="PRO_0000449376"
FT DOMAIN 213..314
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 237
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 239
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 295
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 305
FT /ligand="2-oxoglutarate"
FT /ligand_id="ChEBI:CHEBI:16810"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT BINDING 307
FT /ligand="2-oxoglutarate"
FT /ligand_id="ChEBI:CHEBI:16810"
FT /evidence="ECO:0000250|UniProtKB:D4N500"
SQ SEQUENCE 378 AA; 41620 MW; 9874B329DA043EF6 CRC64;
MAILERAEEA NIGEGSGSSE WELGVRQLCD SGITTLPARY VLPPADRPAR YVTPPALLPV
VDLAALRARD PCQLAALHAA CRDYGFFQLL NHGVPPDAML YAARRFFFDL PLPARKRYMS
ADIRAAVRYG TSFNQLNDAV LSWRDFLKLL IRDTRRLADV LPSWPDAPDD LRPAAAAYAT
ACQRLFRELM EAALDALGIV RCRRQLLEEC DAGSQMMMVN CFPACPEPEL TLGMPPHSDY
GLLTILLQDE VRGLEVSYGD GGGWAVVEPL PGAVVVNVGD HLEILSNGLY RSVLHRVRVN
GRRARVSVAS LHSLAAERVI GPAAELVDEQ RGRPRRYMDT DMAAFLAYLA SAEGNHKSFL
HSRRINTISS SGLTQPSN
