ID   SLD2_PHANO              Reviewed;         470 AA.
AC   Q0UZV8;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=DNA replication regulator SLD2;
GN   Name=SLD2; ORFNames=SNOG_02706;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: Has a role in the initiation of DNA replication. Required at
CC       S-phase checkpoint (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLD2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAT89437.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH445328; EAT89437.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001793303.1; XM_001793251.1.
DR   AlphaFoldDB; Q0UZV8; -.
DR   SMR; Q0UZV8; -.
DR   STRING; 13684.SNOT_02706; -.
DR   GeneID; 5970160; -.
DR   KEGG; pno:SNOG_02706; -.
DR   eggNOG; KOG3151; Eukaryota.
DR   InParanoid; Q0UZV8; -.
DR   OMA; EAHANYR; -.
DR   OrthoDB; 247937at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031261; C:DNA replication preinitiation complex; IBA:GO_Central.
DR   GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IBA:GO_Central.
DR   GO; GO:1902977; P:mitotic DNA replication preinitiation complex assembly; IBA:GO_Central.
DR   InterPro; IPR021110; DNA_rep_checkpnt_protein.
DR   InterPro; IPR040203; Sld2.
DR   PANTHER; PTHR28124; PTHR28124; 1.
DR   Pfam; PF11719; Drc1-Sld2; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cytoplasm; DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..470
FT                   /note="DNA replication regulator SLD2"
FT                   /id="PRO_0000278438"
FT   REGION          52..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          162..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          285..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          451..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..176
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..382
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        401..435
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   470 AA;  52491 MW;  1A1A91586388A6EA CRC64;
     MSITETEQRC NELRNDLKLW EKNFAAQNDG RKAGRDDIKA NEEISNKYKE YNKLRGKLTA
     QSAPQTPSKR TASRKATRDA ERTPKAAPKY QTSTPLKRKR AEELASEPIP QSPEFLSPQG
     PSVIGPTPQR DGIVLGLFDM LPAGTPSKRR AVLGDVELNI LQTPSRRSQE AASETSLESR
     ARGERTPVSV GKRFMLNQFV TPKKRKMEEE GTPSSTTRGL ATPAFLRRGN LLGPIDEADE
     TTPRPAPWKR RGLGRSLSAM IQAMKKDEDD KLDEEADIMR EMEMEEAGIS MPPKKLRVPQ
     ILVEDSQAAM PLGPDRGLET EEDEDEEPEL GPDGKPRRVW KKKGLKRQTR RVIMRPNFIK
     SKLESALQLH DDSEDDQDKV AETQATGHAA DDVDSEDDIS DYASDVSHTP KQRKVQKKKT
     EEVKDQPKEG GVKTAARKIK ATAHANFRRL KIKSSTGAKG GAKGKFGRRR