ID   SLD5_CHAGB              Reviewed;         221 AA.
AC   Q2HE71;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=DNA replication complex GINS protein SLD5;
GN   Name=SLD5; ORFNames=CHGG_01483;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. Has a role in chromosome segregation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS4/SLD5 family. {ECO:0000305}.
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DR   EMBL; CH408029; EAQ93248.1; -; Genomic_DNA.
DR   RefSeq; XP_001220704.1; XM_001220703.1.
DR   AlphaFoldDB; Q2HE71; -.
DR   SMR; Q2HE71; -.
DR   STRING; 38033.XP_001220704.1; -.
DR   EnsemblFungi; EAQ93248; EAQ93248; CHGG_01483.
DR   GeneID; 4387461; -.
DR   eggNOG; KOG3176; Eukaryota.
DR   HOGENOM; CLU_071893_1_1_1; -.
DR   InParanoid; Q2HE71; -.
DR   OMA; ILETAWI; -.
DR   OrthoDB; 1434266at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR   CDD; cd11711; GINS_A_Sld5; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR008591; GINS_Sld5.
DR   InterPro; IPR031633; SLD5_C.
DR   InterPro; IPR038749; Sld5_GINS_A.
DR   PANTHER; PTHR21206; PTHR21206; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   Pfam; PF16922; SLD5_C; 1.
DR   PIRSF; PIRSF007764; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   Chromosome partition; DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..221
FT                   /note="DNA replication complex GINS protein SLD5"
FT                   /id="PRO_0000255430"
SQ   SEQUENCE   221 AA;  25295 MW;  AEE3DAFF55C5C990 CRC64;
     MDIDDILREV DPTFHSIPQE KRDLQELTRA WIAERSAPEL LAWPADGLFE RINDNIKQQI
     EKVEEMTGDM DPKTNFALIV IQTELERYRY LVRSYLRARI AKIDRHTLHY LSTDDLRARL
     SEMELAYATR HQALLHNHYL SSFLSSFPAN LQNLNDAAAG ISMIETPDLE SAVFIRALKD
     TPVEARGVDT DAYADLKESD IVILRWADAK KLVEAGTAEL V