ID   SLD7_KLULA              Reviewed;         260 AA.
AC   Q6CJS0;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Mitochondrial morphogenesis protein SLD7;
GN   Name=SLD7; OrderedLocusNames=KLLA0F16445g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for the proper initiation of DNA replication.
CC       Required for mitochondrial morphology (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       spindle pole {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLD7 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG98527.1; -; Genomic_DNA.
DR   RefSeq; XP_455819.1; XM_455819.1.
DR   AlphaFoldDB; Q6CJS0; -.
DR   SMR; Q6CJS0; -.
DR   STRING; 28985.XP_455819.1; -.
DR   EnsemblFungi; CAG98527; CAG98527; KLLA0_F16445g.
DR   GeneID; 2895666; -.
DR   KEGG; kla:KLLA0_F16445g; -.
DR   eggNOG; ENOG502RZIJ; Eukaryota.
DR   HOGENOM; CLU_072105_0_0_1; -.
DR   InParanoid; Q6CJS0; -.
DR   OMA; EFTHRDE; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:EnsemblFungi.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0031261; C:DNA replication preinitiation complex; IEA:EnsemblFungi.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0030174; P:regulation of DNA-templated DNA replication initiation; IEA:EnsemblFungi.
DR   InterPro; IPR016808; Sld7.
DR   InterPro; IPR041260; Sld7_C.
DR   InterPro; IPR041564; Sld7_N.
DR   Pfam; PF18596; Sld7_C; 1.
DR   Pfam; PF18636; Sld7_N; 1.
DR   PIRSF; PIRSF022788; UCP022788; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cytoplasm; Cytoskeleton; DNA replication; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..260
FT                   /note="Mitochondrial morphogenesis protein SLD7"
FT                   /id="PRO_0000411026"
SQ   SEQUENCE   260 AA;  30313 MW;  98ECCF52F9D1B63E CRC64;
     MTLEKELILR LNVGHNTVIR DVQLWREFED GDGQIAVKNC LAEVVGMVNI DKLPFWLNRG
     QRYQCFTTSE TSVNYFRAKL MRQRHRNRGI VCKVTGSQVL TKEQFEYFLF YKRLKTDINA
     SFEIESMVLH LSTKHELDKK LIPLSADELQ SVVPSNAGAT MSIESILEKN KRQRILKSNS
     LNKQVLLNDQ QQQFMSLLSQ CILSGLRLRG VHRTQHEKLY KMTYKASEFA FRDELRETEP
     ISFESIQDCV ETLLKLFTKT