ID   SLD7_YEAS1              Reviewed;         257 AA.
AC   B3LJA9;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 27.
DE   RecName: Full=Mitochondrial morphogenesis protein SLD7;
DE   AltName: Full=Synthetic lethality with DPB11-24 mutation protein 7;
GN   Name=SLD7; ORFNames=SCRG_01459;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the proper function of SLD3 at the initiation of
CC       DNA replication. Binds to SLD3 and reduces its affinity for CDC45, a
CC       component of the replication fork. Required for mitochondrial
CC       morphology (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with SLD3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       spindle pole {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLD7 family. {ECO:0000305}.
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DR   EMBL; CH408045; EDV10662.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LJA9; -.
DR   SMR; B3LJA9; -.
DR   EnsemblFungi; EDV10662; EDV10662; SCRG_01459.
DR   HOGENOM; CLU_072105_0_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0030174; P:regulation of DNA-templated DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR016808; Sld7.
DR   InterPro; IPR041260; Sld7_C.
DR   InterPro; IPR041564; Sld7_N.
DR   Pfam; PF18596; Sld7_C; 1.
DR   Pfam; PF18636; Sld7_N; 1.
DR   PIRSF; PIRSF022788; UCP022788; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cytoplasm; Cytoskeleton; DNA replication; Nucleus.
FT   CHAIN           1..257
FT                   /note="Mitochondrial morphogenesis protein SLD7"
FT                   /id="PRO_0000411029"
SQ   SEQUENCE   257 AA;  29496 MW;  D366544A3847D817 CRC64;
     MSRKLCTLNF TLSGKQGSLV IRDIQLWSNR PTASKSTSEL RGQFIQYVDL AKLPLWVRST
     NMNTYRCYST SATAQAYFKS KLRNANRGIV IELSDKVDQR SQEPAYLIIF RENTELNCFQ
     VDLTMKHEFD GQVTKLKQEI GKTRASVSKE GSIDIIIQQS QQRKIGTKTK VYRNVHINDK
     RLQFNETLSK LILGGLRLRG ISNSITDYQK LYKVTFDAAE FTHRDELKRI SMGSGEEVSF
     ESLQETVETL LKLFTKS