ID   SLD7_YEAS2              Reviewed;         257 AA.
AC   C7GX58;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   03-AUG-2022, entry version 22.
DE   RecName: Full=Mitochondrial morphogenesis protein SLD7;
DE   AltName: Full=Synthetic lethality with DPB11-24 mutation protein 7;
GN   Name=SLD7; ORFNames=C1Q_05096;
OS   Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=574961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAY291;
RX   PubMed=19812109; DOI=10.1101/gr.091777.109;
RA   Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA   Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA   Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA   Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA   Pereira G.A.G.;
RT   "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT   bioethanol production.";
RL   Genome Res. 19:2258-2270(2009).
CC   -!- FUNCTION: Required for the proper function of SLD3 at the initiation of
CC       DNA replication. Binds to SLD3 and reduces its affinity for CDC45, a
CC       component of the replication fork. Required for mitochondrial
CC       morphology (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with SLD3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       spindle pole {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLD7 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACFL01000407; EEU04616.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7GX58; -.
DR   SMR; C7GX58; -.
DR   Proteomes; UP000008073; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0030174; P:regulation of DNA-templated DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR016808; Sld7.
DR   InterPro; IPR041260; Sld7_C.
DR   InterPro; IPR041564; Sld7_N.
DR   Pfam; PF18596; Sld7_C; 1.
DR   Pfam; PF18636; Sld7_N; 1.
DR   PIRSF; PIRSF022788; UCP022788; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cytoplasm; Cytoskeleton; DNA replication; Nucleus.
FT   CHAIN           1..257
FT                   /note="Mitochondrial morphogenesis protein SLD7"
FT                   /id="PRO_0000411030"
SQ   SEQUENCE   257 AA;  29570 MW;  9277545FB7239CCC CRC64;
     MSRKLCTLNF TLSGKQGSLV IRDIQLWSNR PTASKSTSEL RGQFIQYVDL AKLPLWVRST
     NMNTYRCYST SATAQAYFKS KLRNANRGIV IELFDKVDQR SQEPAYLIIF RENTELNCFQ
     VDLTMKHEFD GQVTKLKQEI GKTRASVSKE GSIDIIIQQS QQRKIGTKTK VYRNVHINDK
     RLQFNETLSK LILGGLRLRG ISNSITDYQK LYKITFDAAE FTHRDELKRI SMGSGEEVSF
     ESLQETVETL LKLFTKS