SLD7_YEAS6
ID SLD7_YEAS6 Reviewed; 257 AA.
AC B5VRV8;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 26.
DE RecName: Full=Mitochondrial morphogenesis protein SLD7;
DE AltName: Full=Synthetic lethality with DPB11-24 mutation protein 7;
GN Name=SLD7; ORFNames=AWRI1631_152200;
OS Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=545124;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI1631;
RX PubMed=18778279; DOI=10.1111/j.1567-1364.2008.00434.x;
RA Borneman A.R., Forgan A.H., Pretorius I.S., Chambers P.J.;
RT "Comparative genome analysis of a Saccharomyces cerevisiae wine strain.";
RL FEMS Yeast Res. 8:1185-1195(2008).
CC -!- FUNCTION: Required for the proper function of SLD3 at the initiation of
CC DNA replication. Binds to SLD3 and reduces its affinity for CDC45, a
CC component of the replication fork. Required for mitochondrial
CC morphology (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with SLD3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC spindle pole {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLD7 family. {ECO:0000305}.
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DR EMBL; ABSV01002141; EDZ69334.1; -; Genomic_DNA.
DR AlphaFoldDB; B5VRV8; -.
DR SMR; B5VRV8; -.
DR Proteomes; UP000008988; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0030174; P:regulation of DNA-templated DNA replication initiation; IEA:InterPro.
DR InterPro; IPR016808; Sld7.
DR InterPro; IPR041260; Sld7_C.
DR InterPro; IPR041564; Sld7_N.
DR Pfam; PF18596; Sld7_C; 1.
DR Pfam; PF18636; Sld7_N; 1.
DR PIRSF; PIRSF022788; UCP022788; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cytoplasm; Cytoskeleton; DNA replication; Nucleus.
FT CHAIN 1..257
FT /note="Mitochondrial morphogenesis protein SLD7"
FT /id="PRO_0000411031"
SQ SEQUENCE 257 AA; 29510 MW; D366545310E54B17 CRC64;
MSRKLCTLNF TLSGKQGSLV IRDIQLWSNR PTASKSTSEL RGQFIQYVDL AKLPLWVRST
NMNTYRCYST SATAQAYFKS KLRNANRGIV IELSDKVDQR SQEPAYLIIF RENTELNCFQ
VDLTMKHEFD GQVTKLKQEI GKTRASVSKE GSIDIIIQQS QQRKIGTKTK VYRNVHINDK
RLQFNETLSK LILGGLRLRG ISNSITDYQK LYKITFDAAE FTHRDELKRI SMGSGEEVSF
ESLQETVETL LKLFTKS