ID   SLD7_YEAS7              Reviewed;         257 AA.
AC   A6ZNR2;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 29.
DE   RecName: Full=Mitochondrial morphogenesis protein SLD7;
DE   AltName: Full=Synthetic lethality with DPB11-24 mutation protein 7;
GN   Name=SLD7; ORFNames=SCY_5130;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Required for the proper function of SLD3 at the initiation of
CC       DNA replication. Binds to SLD3 and reduces its affinity for CDC45, a
CC       component of the replication fork. Required for mitochondrial
CC       morphology (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with SLD3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       spindle pole {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLD7 family. {ECO:0000305}.
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DR   EMBL; AAFW02000030; EDN63927.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZNR2; -.
DR   SMR; A6ZNR2; -.
DR   EnsemblFungi; EDN63927; EDN63927; SCY_5130.
DR   HOGENOM; CLU_072105_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0030174; P:regulation of DNA-templated DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR016808; Sld7.
DR   InterPro; IPR041260; Sld7_C.
DR   InterPro; IPR041564; Sld7_N.
DR   Pfam; PF18596; Sld7_C; 1.
DR   Pfam; PF18636; Sld7_N; 1.
DR   PIRSF; PIRSF022788; UCP022788; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cytoplasm; Cytoskeleton; DNA replication; Nucleus.
FT   CHAIN           1..257
FT                   /note="Mitochondrial morphogenesis protein SLD7"
FT                   /id="PRO_0000411032"
SQ   SEQUENCE   257 AA;  29510 MW;  D366545310E54B17 CRC64;
     MSRKLCTLNF TLSGKQGSLV IRDIQLWSNR PTASKSTSEL RGQFIQYVDL AKLPLWVRST
     NMNTYRCYST SATAQAYFKS KLRNANRGIV IELSDKVDQR SQEPAYLIIF RENTELNCFQ
     VDLTMKHEFD GQVTKLKQEI GKTRASVSKE GSIDIIIQQS QQRKIGTKTK VYRNVHINDK
     RLQFNETLSK LILGGLRLRG ISNSITDYQK LYKITFDAAE FTHRDELKRI SMGSGEEVSF
     ESLQETVETL LKLFTKS