BI1_ORYSJ
ID BI1_ORYSJ Reviewed; 249 AA.
AC Q9MBD8; Q0E4C9; Q6Z2N7; Q6Z2N8;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Bax inhibitor 1;
DE Short=BI-1;
DE AltName: Full=OsBI-1;
GN Name=BI1; OrderedLocusNames=Os02g0125300, LOC_Os02g03280;
GN ORFNames=P0482F12.1-1, P0482F12.1-2;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Yamahoushi;
RX PubMed=10618494; DOI=10.1016/s0014-5793(99)01695-6;
RA Kawai M., Pan L., Reed J.C., Uchimiya H.;
RT "Evolutionally conserved plant homologue of the Bax inhibitor-1 (BI-1) gene
RT capable of suppressing Bax-induced cell death in yeast.";
RL FEBS Lett. 464:143-147(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Suppressor of apoptosis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Ubiquitous.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD08007.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB025926; BAA89540.3; -; mRNA.
DR EMBL; AP005311; BAD08006.1; -; Genomic_DNA.
DR EMBL; AP005311; BAD08007.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAF07659.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS76758.1; -; Genomic_DNA.
DR EMBL; AK061564; BAG88010.1; -; mRNA.
DR EMBL; AK101060; BAG94894.1; -; mRNA.
DR RefSeq; XP_015625700.1; XM_015770214.1.
DR AlphaFoldDB; Q9MBD8; -.
DR SMR; Q9MBD8; -.
DR STRING; 4530.OS02T0125300-01; -.
DR PaxDb; Q9MBD8; -.
DR PRIDE; Q9MBD8; -.
DR EnsemblPlants; Os02t0125300-01; Os02t0125300-01; Os02g0125300.
DR EnsemblPlants; Os02t0125300-02; Os02t0125300-02; Os02g0125300.
DR GeneID; 4328149; -.
DR Gramene; Os02t0125300-01; Os02t0125300-01; Os02g0125300.
DR Gramene; Os02t0125300-02; Os02t0125300-02; Os02g0125300.
DR KEGG; osa:4328149; -.
DR eggNOG; KOG1629; Eukaryota.
DR HOGENOM; CLU_061277_1_0_1; -.
DR InParanoid; Q9MBD8; -.
DR OMA; FSCAAIV; -.
DR OrthoDB; 1275249at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q9MBD8; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR InterPro; IPR006213; Bax_inhbtr1_CS.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291; PTHR23291; 1.
DR Pfam; PF01027; Bax1-I; 1.
DR PROSITE; PS01243; BI1; 1.
PE 2: Evidence at transcript level;
KW Apoptosis; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..249
FT /note="Bax inhibitor 1"
FT /id="PRO_0000179086"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 249 AA; 27114 MW; FEAE334173F6D384 CRC64;
MDAFYSTSSA YGAAASGWGY DSLKNFRQIS PAVQSHLKLV YLTLCVALAA SAVGAYLHVA
LNIGGMLTML GCVGSIAWLF SVPVFEERKR FGILLAAALL EGASVGPLIK LAVDFDSSIL
VTAFVGTAIA FGCFTCAAIV AKRREYLYLG GLLSSGLSIL LWLQFAASIF GHSTGSFMFE
VYFGLLIFLG YMVYDTQEII ERAHHGDMDY IKHALTLFTD FVAVLVRILV IMLKNASDKS
EEKKRKKRS
