SLDB_GLUOX
ID SLDB_GLUOX Reviewed; 126 AA.
AC Q70JP0; Q5FSL7;
DT 24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Glycerol dehydrogenase small subunit;
DE EC=1.1.99.22;
DE AltName: Full=D-arabitol dehydrogenase small subunit;
DE Short=ARDH;
DE AltName: Full=D-sorbitol dehydrogenase subunit SldB;
DE Short=SLDH;
DE AltName: Full=Gluconate/polyol dehydrogenase small subunit;
GN Name=sldB; Synonyms=g5dhA; OrderedLocusNames=GOX0855;
OS Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Gluconobacter.
OX NCBI_TaxID=290633;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 621 / DSM 50049 / NBRC 3172 / NCIMB 7069 / NRRL B-72;
RX PubMed=15060755; DOI=10.1007/s00253-004-1594-6;
RA Salusjaervi T., Povelainen M., Hvorslev N., Eneyskaya E.E.,
RA Kulminskaya A.A., Shabalin K.A., Neustroev K.N., Kalkkinen N.,
RA Miasnikov A.N.;
RT "Cloning of a gluconate/polyol dehydrogenase gene from Gluconobacter
RT suboxydans IFO 12528, characterisation of the enzyme and its use for the
RT production of 5-ketogluconate in a recombinant Escherichia coli strain.";
RL Appl. Microbiol. Biotechnol. 65:306-314(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=621H;
RX PubMed=15665824; DOI=10.1038/nbt1062;
RA Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F.,
RA Ehrenreich A., Gottschalk G., Deppenmeier U.;
RT "Complete genome sequence of the acetic acid bacterium Gluconobacter
RT oxydans.";
RL Nat. Biotechnol. 23:195-200(2005).
CC -!- FUNCTION: Catalyzes the oxidation of glycerol to glycerone. Also acts,
CC more slowly, on a number of other polyols including D-sorbitol, D-
CC arabinitol, D-mannitol, meso-erythritol, adonitol and propylene glycol
CC (By similarity). {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=A + glycerol = AH2 + dihydroxyacetone; Xref=Rhea:RHEA:17493,
CC ChEBI:CHEBI:13193, ChEBI:CHEBI:16016, ChEBI:CHEBI:17499,
CC ChEBI:CHEBI:17754; EC=1.1.99.22;
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AJ577472; CAE12057.1; -; Genomic_DNA.
DR EMBL; CP000009; AAW60629.1; -; Genomic_DNA.
DR RefSeq; WP_011252425.1; NZ_LT900338.1.
DR AlphaFoldDB; Q70JP0; -.
DR STRING; 290633.GOX0855; -.
DR EnsemblBacteria; AAW60629; AAW60629; GOX0855.
DR GeneID; 56905171; -.
DR KEGG; gox:GOX0855; -.
DR eggNOG; COG4993; Bacteria.
DR HOGENOM; CLU_146618_0_0_5; -.
DR BRENDA; 1.1.1.69; 38.
DR BRENDA; 1.1.99.21; 38.
DR Proteomes; UP000006375; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0047955; F:glycerol dehydrogenase (acceptor) activity; IEA:UniProtKB-EC.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Oxidoreductase; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..126
FT /note="Glycerol dehydrogenase small subunit"
FT /id="PRO_0000076319"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 126 AA; 13724 MW; 16DB804354615412 CRC64;
MPNTYGSRTL TEWLTLVLGV VIILVGLFFV IAGADLAMLG GSVYYVICGI PLVAGGVFML
MGRTLGAFLY LGALAYTWVW SLWEVGFSPV DLLPRDFGPT LLGILVALTI PVLRRMETRR
TLRGTV
