ID   SLEB_OCEIH              Reviewed;         276 AA.
AC   P59105;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2002, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Spore cortex-lytic enzyme;
DE            Short=SCLE;
DE   Flags: Precursor;
GN   Name=sleB; OrderedLocusNames=OB1806;
OS   Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS   3954 / HTE831).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=221109;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831;
RX   PubMed=12235376; DOI=10.1093/nar/gkf526;
RA   Takami H., Takaki Y., Uchiyama I.;
RT   "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT   and its unexpected adaptive capabilities to extreme environments.";
RL   Nucleic Acids Res. 30:3927-3935(2002).
CC   -!- FUNCTION: Required for spore cortex hydrolysis during germination.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SleB family. {ECO:0000305}.
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DR   EMBL; BA000028; BAC13762.1; -; Genomic_DNA.
DR   RefSeq; WP_011066204.1; NC_004193.1.
DR   AlphaFoldDB; P59105; -.
DR   SMR; P59105; -.
DR   STRING; 221109.22777490; -.
DR   EnsemblBacteria; BAC13762; BAC13762; BAC13762.
DR   KEGG; oih:OB1806; -.
DR   eggNOG; COG3409; Bacteria.
DR   eggNOG; COG3773; Bacteria.
DR   HOGENOM; CLU_053345_0_0_9; -.
DR   OMA; KTYMAVR; -.
DR   OrthoDB; 682655at2; -.
DR   Proteomes; UP000000822; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0009847; P:spore germination; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.2520; -; 1.
DR   Gene3D; 1.10.101.10; -; 1.
DR   InterPro; IPR011105; Cell_wall_hydrolase_SleB.
DR   InterPro; IPR002477; Peptidoglycan-bd-like.
DR   InterPro; IPR036365; PGBD-like_sf.
DR   InterPro; IPR036366; PGBDSf.
DR   InterPro; IPR042047; SleB_dom1.
DR   InterPro; IPR014224; Spore_cortex_SleB.
DR   Pfam; PF07486; Hydrolase_2; 1.
DR   Pfam; PF01471; PG_binding_1; 1.
DR   SUPFAM; SSF47090; SSF47090; 1.
DR   TIGRFAMs; TIGR02869; spore_SleB; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Germination; Hydrolase;
KW   Reference proteome; Signal; Sporulation.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..276
FT                   /note="Spore cortex-lytic enzyme"
FT                   /id="PRO_0000022359"
FT   REGION          118..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   276 AA;  30363 MW;  DB1DA640BBEE3CF6 CRC64;
     MHQSYKAFMI ILVVCSSLTM YFTQTDNTKT YAFSDQVIQQ GAVGEDVIEL QARLQYLGFY
     NGKIDGVFGW GTYWALRNFQ YEFGMEIDGL AGQTTKDKLV QASNYDKEYV TEQINKGNQF
     THYGGGDRNT DGQSNSGGGS GNSGEDTGGT PSVNVPQGYS QNDIQLMANA VYGEARGEPY
     EGQVAVAAVI LNRLNSALFP DTVSGVIFEP RAFTAVADGQ IWLEPNDKAR EAVLDAINGW
     DPSGNALYYF NPDTATSGWI WTRPQIKQIG KHIFCK