ID   SLP2_YEAS7              Reviewed;         148 AA.
AC   A6ZT44;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Putative cyclin-dependent kinase inhibitor SPL2;
DE   AltName: Full=Suppressor of PLC1 deletion protein 2;
GN   Name=SPL2; ORFNames=SCY_2528;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Putative cyclin-dependent kinase (CDK) inhibitor necessary
CC       and sufficient for PHO pathway-dependent down-regulation of low-
CC       affinity phosphate transport.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic granule. Cytoplasm.
CC   -!- INDUCTION: Regulated by phosphate, probably through its PHO4-binding
CC       elements in the promoter.
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DR   EMBL; AAFW02000082; EDN62375.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZT44; -.
DR   EnsemblFungi; EDN62375; EDN62375; SCY_2528.
DR   HOGENOM; CLU_2051493_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Phosphoprotein; Protein kinase inhibitor.
FT   CHAIN           1..148
FT                   /note="Putative cyclin-dependent kinase inhibitor SPL2"
FT                   /id="PRO_0000333463"
FT   MOD_RES         59
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P38839"
FT   MOD_RES         86
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P38839"
SQ   SEQUENCE   148 AA;  17121 MW;  B24160F8DDE3DA4B CRC64;
     MRTYTPLIYN IYNVHIWVFT ESQGQIGQMS PRGKMETAVS QGQHKQLKDG HQHKGRKLSE
     EIASLLRLKE CRRLNPASYY TPRRTSQSQS LSGSTFKEYN EYVNEKDSSR AQRQNAAAVL
     SKLAHDFWEN DCVIDEDIFE DSSDEEQS