ID   SLP3_PINMA              Reviewed;         343 AA.
AC   P86951;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-OCT-2011, sequence version 1.
DT   25-MAY-2022, entry version 16.
DE   RecName: Full=Shematrin-like protein 3;
DE   Flags: Precursor;
OS   Pinctada maxima (Silver-lipped pearl oyster) (White-lipped pearl oyster).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Pterioida; Pterioidea; Pteriidae; Pinctada.
OX   NCBI_TaxID=104660;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND IDENTIFICATION.
RC   TISSUE=Mantle {ECO:0000269|PubMed:19915030};
RX   PubMed=19915030; DOI=10.1093/molbev/msp278;
RA   Jackson D.J., McDougall C., Woodcroft B., Moase P., Rose R.A., Kube M.,
RA   Reinhardt R., Rokhsar D.S., Montagnani C., Joubert C., Piquemal D.,
RA   Degnan B.M.;
RT   "Parallel evolution of nacre building gene sets in molluscs.";
RL   Mol. Biol. Evol. 27:591-608(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 98-130, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Shell;
RX   PubMed=23213212; DOI=10.1073/pnas.1210552109;
RA   Marie B., Joubert C., Tayale A., Zanella-Cleon I., Belliard C.,
RA   Piquemal D., Cochennec-Laureau N., Marin F., Gueguen Y., Montagnani C.;
RT   "Different secretory repertoires control the biomineralization processes of
RT   prism and nacre deposition of the pearl oyster shell.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:20986-20991(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23213212}.
CC   -!- TISSUE SPECIFICITY: Prismatic layer of shell (at protein level).
CC       {ECO:0000269|PubMed:23213212}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GT279033; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; GT279081; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; GT279728; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; GT281300; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; GT281620; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; GT284145; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; EZ420249; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P86951; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..343
FT                   /note="Shematrin-like protein 3"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000413086"
FT   CONFLICT        149
FT                   /note="G -> V (in Ref. 1; GT279728)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        165
FT                   /note="G -> R (in Ref. 1; GT279081)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        192
FT                   /note="S -> N (in Ref. 1; GT281300)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   343 AA;  32074 MW;  8C1EBE7E8563B4C2 CRC64;
     MLKLVCAVVL IATVNAKGSS PGFGIGQLPG ITVVSGGVSG GSLSGGVSGG SLSGGIYGGY
     PRLYGGFGPG GVYGSINSFG GVNTNAYGLY GTSPAVRGAA QGAAATSVLG ILSGVPSRIS
     GYSVGTGGGR AFVSGSATPI GGLPYGGYGY GGYGYGGYGG YGYGGYGYPD IAYYGGSTYG
     NIASGVISSP TSGVSLPYGG ILGLYGGYGG YGSGYGGYGM GSAYSIGNYL SGHGGYYGGS
     YPSYGSTLTG VSQSLSFGRA IMSGQAFGAG VPAFGSVNFG NFGVGTGGIG ILGGGGVIGS
     GGVIGGGGVI GGGGVVGGGA VIGGGGVIGG GVPTGGIIRK KKY