SLR1_ORYSI
ID SLR1_ORYSI Reviewed; 625 AA.
AC Q2TN88; A2XL69;
DT 16-MAR-2016, integrated into UniProtKB/Swiss-Prot.
DT 16-MAR-2016, sequence version 2.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=DELLA protein SLR1 {ECO:0000305};
DE AltName: Full=Gibberellic acid-insensitive {ECO:0000303|Ref.1};
DE AltName: Full=OsGAI {ECO:0000303|Ref.1};
DE AltName: Full=Protein SLENDER RICE1 {ECO:0000305};
GN Name=SLR1 {ECO:0000305}; Synonyms=GAI {ECO:0000303|Ref.1};
GN ORFNames=OsI_13213 {ECO:0000312|EMBL:EAY91579.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946 {ECO:0000312|EMBL:AAX07462.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Chowdhury A.H., Bhattacharyya J., Maiti M.K., Basu A., Sen S.K.;
RT "Functional characterization of gibberellic acid insensitive (GAI) gene and
RT its promoter from indica rice.";
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Probable transcriptional regulator that acts as a repressor
CC of the gibberellin (GA) signaling pathway. Probably acts by
CC participating in large multiprotein complexes that repress
CC transcription of GA-inducible genes. Upon GA application, it is
CC degraded by the proteasome, allowing the GA signaling pathway. In
CC contrast, its overexpression prevents the GA signaling pathway and
CC induces a dwarf phenotype. {ECO:0000250|UniProtKB:Q7G7J6}.
CC -!- DOMAIN: The DELLA motif is required for its GA-induced degradation.
CC {ECO:0000250|UniProtKB:Q7G7J6}.
CC -!- SIMILARITY: Belongs to the GRAS family. DELLA subfamily. {ECO:0000305}.
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DR EMBL; AY781175; AAX07462.1; -; Genomic_DNA.
DR EMBL; CM000128; EAY91579.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2TN88; -.
DR SMR; Q2TN88; -.
DR STRING; 39946.Q2TN88; -.
DR EnsemblPlants; BGIOSGA013420-TA; BGIOSGA013420-PA; BGIOSGA013420.
DR Gramene; BGIOSGA013420-TA; BGIOSGA013420-PA; BGIOSGA013420.
DR OMA; VQQENFA; -.
DR Proteomes; UP000007015; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblPlants.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR Gene3D; 1.10.10.1290; -; 1.
DR InterPro; IPR038088; DELLA_N_sf.
DR InterPro; IPR030006; TF_DELLA.
DR InterPro; IPR021914; TF_DELLA_N.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 1.
DR PANTHER; PTHR31636:SF47; PTHR31636:SF47; 1.
DR Pfam; PF12041; DELLA; 1.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 3: Inferred from homology;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..625
FT /note="DELLA protein SLR1"
FT /id="PRO_0000435824"
FT DOMAIN 232..621
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..294
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 241..278
FT /note="Required for possible homodimerization"
FT /evidence="ECO:0000250|UniProtKB:Q7G7J6"
FT REGION 313..378
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 392..431
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 441..542
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 545..621
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 39..43
FT /note="DELLA motif"
FT /evidence="ECO:0000250|UniProtKB:Q7G7J6"
FT MOTIF 246..250
FT /note="LxCxE motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 344..348
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 449..453
FT /note="LXXLL motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COMPBIAS 182..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 71
FT /note="G -> A (in Ref. 1; AAX07462)"
SQ SEQUENCE 625 AA; 65455 MW; 4A8E66B842869225 CRC64;
MKREYQEAGG SSGGGSSADM GSCKDKVMAG AAGEEEDVDE LLAALGYKVR SSDMADVAQK
LEQLEMAMGM GGVSAPGAAD DGFVSHLATD TVHYNPSDLS SWVESMLSEL NAPLPPIPPA
PPAARHASTS STVTGGGGSG FFELPAAADS SSSTYALRPI SLPVVATADP SAADSARDTK
RMRTGGGSTS SSSSSSSSLG GGASRGSVVE AAPPAMQGAA AANAPAVPVV VVDTQEAGIR
LVHALLACAE AVQQENFAAA EALVKQIPTL AASQGGAMRK VAAYFGEALA RRVYRFRPAD
STLLDAAFAD LLHAHFYESC PYLKFAHFTA NQAILEAFAG CRRVHVVDFG IKQGMQWPAL
LQALALRPGG PPSFRLTGVG PPQPDETDAL QQVGWKLAQF AHTIRVDFQY RGLVAATLAD
LEPFMLQPEG EADANEEPEV IAVNSVFELH RLLAQPGALE KVLGTVHAVR PRIVTVVEQE
ANHNSGSFLD RFTESLHYYS TMFDSLEGGS SGQAELSPPA AGGGGGTDQV MSEVYLGRQI
CNVVACEGAE RTERHETLGQ WRNRLGRAGF EPVHLGSNAY KQASTLLALF AGGDGYRVEE
KEGCLTLGWH TRPLIATSAW RVAAA
