ID   SLRA_BACSU              Reviewed;          52 AA.
AC   P0C8M5; C0H3S7;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Transcriptional regulator SlrA;
GN   Name=slrA; OrderedLocusNames=BSU38229;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   IDENTIFICATION, FUNCTION, SUBUNIT, AND DISRUPTION PHENOTYPE.
RX   PubMed=18647168; DOI=10.1111/j.1365-2958.2008.06369.x;
RA   Kobayashi K.;
RT   "SlrR/SlrA controls the initiation of biofilm formation in Bacillus
RT   subtilis.";
RL   Mol. Microbiol. 69:1399-1410(2008).
CC   -!- FUNCTION: Required specifically for induction of eps and yqxM operons
CC       by antagonizing SinR. Regulates SlrR activity. Controls the initiation
CC       of biofilm formation. {ECO:0000269|PubMed:18647168}.
CC   -!- SUBUNIT: Component of the SlrR/SlrA complex.
CC       {ECO:0000269|PubMed:18647168}.
CC   -!- DISRUPTION PHENOTYPE: Defective in biofilm formation.
CC       {ECO:0000269|PubMed:18647168}.
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DR   EMBL; AL009126; CAX52707.1; -; Genomic_DNA.
DR   RefSeq; WP_003243648.1; NZ_JNCM01000034.1.
DR   RefSeq; YP_003097794.1; NC_000964.3.
DR   AlphaFoldDB; P0C8M5; -.
DR   SMR; P0C8M5; -.
DR   STRING; 224308.BSU38229; -.
DR   PaxDb; P0C8M5; -.
DR   PRIDE; P0C8M5; -.
DR   EnsemblBacteria; CAX52707; CAX52707; BSU_38229.
DR   GeneID; 8303165; -.
DR   KEGG; bsu:BSU38229; -.
DR   PATRIC; fig|224308.179.peg.4138; -.
DR   OMA; PMKNTIR; -.
DR   BioCyc; BSUB:BSU38229-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR010981; SinR/SinI_dimer_dom.
DR   InterPro; IPR036281; SinR/SinI_dimer_dom_sf.
DR   Pfam; PF08671; SinI; 1.
DR   SUPFAM; SSF47406; SSF47406; 1.
DR   PROSITE; PS51500; SIN; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..52
FT                   /note="Transcriptional regulator SlrA"
FT                   /id="PRO_0000360154"
FT   DOMAIN          1..38
FT                   /note="Sin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00833"
SQ   SEQUENCE   52 AA;  6126 MW;  70EB44423A79B6B1 CRC64;
     MKTHVKKDLD KGWHMLIQEA RSIGLGIHDV RQFLESETAS RKKNHKKTVR QD