ID   SLT11_DEBHA             Reviewed;         359 AA.
AC   Q6BMD1;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Pre-mRNA-splicing factor SLT11;
GN   Name=SLT11; OrderedLocusNames=DEHA2F06490g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. Facilitates the cooperative
CC       formation of U2/U6 helix II in association with stem II in the
CC       spliceosome. Binds to RNA (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLT11 family. {ECO:0000305}.
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DR   EMBL; CR382138; CAG88972.2; -; Genomic_DNA.
DR   RefSeq; XP_460640.2; XM_460640.1.
DR   AlphaFoldDB; Q6BMD1; -.
DR   SMR; Q6BMD1; -.
DR   STRING; 4959.XP_460640.2; -.
DR   PRIDE; Q6BMD1; -.
DR   EnsemblFungi; CAG88972; CAG88972; DEHA2F06490g.
DR   GeneID; 2903151; -.
DR   KEGG; dha:DEHA2F06490g; -.
DR   VEuPathDB; FungiDB:DEHA2F06490g; -.
DR   eggNOG; KOG0153; Eukaryota.
DR   HOGENOM; CLU_027112_1_1_1; -.
DR   InParanoid; Q6BMD1; -.
DR   OMA; PYFRKGR; -.
DR   OrthoDB; 1272857at2759; -.
DR   Proteomes; UP000000599; Chromosome F.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   CDD; cd12265; RRM_SLT11; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR039171; Cwc2/Slt11.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR034356; Slt11_RRM.
DR   PANTHER; PTHR14089; PTHR14089; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; RNA-binding;
KW   Spliceosome.
FT   CHAIN           1..359
FT                   /note="Pre-mRNA-splicing factor SLT11"
FT                   /id="PRO_0000212426"
FT   REGION          324..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   359 AA;  40173 MW;  AA6E9506B99F5C3D CRC64;
     MSDEFPAICD SCCGPDKHIK MMRQANGEEC KVCTRPFTVF RWNPNNGTNK SKKTIICMTC
     ARARNCCQSC MLDITYGIPL EIRDTALKMA GLEHASQIKS SNTSQNREVK AIMADKQEAK
     YNNEDNDVNK SNDRSEMARD ILSKLSEKLN GNTNALIKKA PKNSKTTKKN EIINVKNADI
     SKILGKLPLG GSIVVPETTP ELSSFFLFGF SDDIPQYIIS DFCNKFGKIK SLSIVHRAKC
     GYVVFTTRKA AESFATTIME NGLNKNTATP GLLILNNKYP VRVSWGKQKP LVTTNEECHK
     LSLVITKVMR QLAEKDKIFE DQKITKKAKN HKTSSDANEH SSNTASTQHY KALRPDFEL