ID   SLT_ENTCL               Reviewed;          42 AA.
AC   P39433;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Soluble lytic murein transglycosylase;
DE            EC=4.2.2.n1;
DE   AltName: Full=Peptidoglycan lytic exotransglycosylase;
DE   AltName: Full=Slt70;
DE   Flags: Fragment;
GN   Name=slt;
OS   Enterobacter cloacae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX   NCBI_TaxID=550;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8208606; DOI=10.1093/nar/22.10.1821;
RA   Arvidson D.N., Arvidson C.G., Lawson C.L., Miner J., Adams C.,
RA   Youderian P.;
RT   "The tryptophan repressor sequence is highly conserved among the
RT   Enterobacteriaceae.";
RL   Nucleic Acids Res. 22:1821-1829(1994).
CC   -!- FUNCTION: Murein-degrading enzyme. Catalyzes the cleavage of the
CC       glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine
CC       residues in peptidoglycan. May play a role in recycling of muropeptides
CC       during cell elongation and/or cell division (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Exolytic cleavage of the (1->4)-beta-glycosidic linkage
CC         between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine
CC         (GlcNAc) residues in peptidoglycan, from either the reducing or the
CC         non-reducing ends of the peptidoglycan chains, with concomitant
CC         formation of a 1,6-anhydrobond in the MurNAc residue.; EC=4.2.2.n1;
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the transglycosylase Slt family. {ECO:0000305}.
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DR   EMBL; L26583; AAA20182.1; -; Unassigned_DNA.
DR   PIR; S45256; S45256.
DR   AlphaFoldDB; P39433; -.
DR   SMR; P39433; -.
DR   STRING; 1399774.JDWH01000001_gene2466; -.
DR   eggNOG; COG0741; Bacteria.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   SUPFAM; SSF53955; SSF53955; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Lyase; Periplasm.
FT   CHAIN           <1..42
FT                   /note="Soluble lytic murein transglycosylase"
FT                   /id="PRO_0000196559"
FT   NON_TER         1
SQ   SEQUENCE   42 AA;  5095 MW;  D2D1441CB7FC5EEA CRC64;
     ESIPFSETRG YVKNVLAYDA YYRHFMGEKD ALMSDAEWQR RY