SLU7_ASHGO
ID SLU7_ASHGO Reviewed; 266 AA.
AC Q74ZN9;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Pre-mRNA-splicing factor SLU7;
GN Name=SLU7; OrderedLocusNames=AGR159C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
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DR EMBL; AE016820; AAS54649.1; -; Genomic_DNA.
DR RefSeq; NP_986825.1; NM_211887.1.
DR AlphaFoldDB; Q74ZN9; -.
DR STRING; 33169.AAS54649; -.
DR EnsemblFungi; AAS54649; AAS54649; AGOS_AGR159C.
DR GeneID; 4623127; -.
DR KEGG; ago:AGOS_AGR159C; -.
DR eggNOG; KOG2560; Eukaryota.
DR HOGENOM; CLU_072877_0_0_1; -.
DR InParanoid; Q74ZN9; -.
DR Proteomes; UP000000591; Chromosome VII.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR InterPro; IPR039974; Splicing_factor_SLU7.
DR PANTHER; PTHR12942; PTHR12942; 2.
PE 3: Inferred from homology;
KW Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Spliceosome; Zinc; Zinc-finger.
FT CHAIN 1..266
FT /note="Pre-mRNA-splicing factor SLU7"
FT /id="PRO_0000218542"
FT ZN_FING 68..84
FT /note="CCHC-type"
FT REGION 160..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 266 AA; 28924 MW; D34AA550C2575B25 CRC64;
MEENKHIPKY IRDKPWYVES GDDDADYLGH HRREPGEGAQ DFSVAQQGSV ISDRFVAGSA
PRAGRGRGRC TNCGANHDRR DCLLRPRKQA RGDGGERAFQ VRDENALSFE AKRDRWYGFE
GPVAPAVAAA AAEPPAAAED AAAAVERYKL GLDARAARAG VGAPAIRPRH DRARYLDDVR
GEETRYDPKS RVYRGDGAAG EAPAAPDRAG RDGSTVDHVI SANPTRLELG RQTPERGARQ
PEGQAQSAAA RASLLQRYGN SARSRR