ID   SLU7_ASPFU              Reviewed;         476 AA.
AC   Q4WWR2;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 2.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Pre-mRNA-splicing factor slu7;
GN   Name=slu7; ORFNames=AFUA_3G06770;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
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DR   EMBL; AAHF01000002; EAL92891.2; -; Genomic_DNA.
DR   RefSeq; XP_754929.2; XM_749836.2.
DR   AlphaFoldDB; Q4WWR2; -.
DR   SMR; Q4WWR2; -.
DR   STRING; 746128.CADAFUBP00004144; -.
DR   EnsemblFungi; EAL92891; EAL92891; AFUA_3G06770.
DR   GeneID; 3511748; -.
DR   KEGG; afm:AFUA_3G06770; -.
DR   VEuPathDB; FungiDB:Afu3g06770; -.
DR   eggNOG; KOG2560; Eukaryota.
DR   HOGENOM; CLU_019317_3_1_1; -.
DR   InParanoid; Q4WWR2; -.
DR   OMA; KKPFYVD; -.
DR   OrthoDB; 816947at2759; -.
DR   Proteomes; UP000002530; Chromosome 3.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR   InterPro; IPR021715; Slu7_dom.
DR   InterPro; IPR039974; Splicing_factor_SLU7.
DR   PANTHER; PTHR12942; PTHR12942; 1.
DR   Pfam; PF11708; Slu7; 1.
PE   3: Inferred from homology;
KW   Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome; Zinc; Zinc-finger.
FT   CHAIN           1..476
FT                   /note="Pre-mRNA-splicing factor slu7"
FT                   /id="PRO_0000218543"
FT   ZN_FING         70..87
FT                   /note="CCHC-type"
FT   REGION          396..476
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        415..463
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   476 AA;  54316 MW;  EECA1154DC1D2C67 CRC64;
     MSRKPADVAS KERNEYIPSF IAKKPFYIDD ESTANDYLEH QRLQKQATDQ SKWYDRGKRA
     GPAATKYRKG ACENCGAMTH KSKECLSRPR KLGAKWTGKD IQADEVVQNV ELGWDAKRDR
     WNGYDPSEYR QVIEEYEELE KLKRNTKPGA QDGKKIMDGE LDDEEAAIEE ARYAEESDMG
     RQQSTATRNL RIREDTAKYL LNLDLDSAKY DPKTRRMVDM GAQDDQAAAL VAEENFVRAS
     GDAAEFERAQ RYAWESQERG DKKIHLQANP TSGEILRKKE QAETEAKRQA QRKALLEKYG
     GEEYLKPTPL RETMVIENER FVEYDESGAI KGAPKNAVKS KYPEDVLVNN HTTVFGSWWH
     NFQWGYACCF STVKNSYCTG EDGKKAFEEA EMRSMGLLPG PETSDQTSPP AKGETNDIHE
     AEDLSDRSQR KADTETNTRK RTMMEMKSGV SEEELESYKR SRLAADDPMA SFIGKE