ID   SLU7_CANAL              Reviewed;         350 AA.
AC   Q5ADL4; A0A1D8PKP7;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Pre-mRNA-splicing factor SLU7;
GN   Name=SLU7; OrderedLocusNames=CAALFM_C306770WA;
GN   ORFNames=CaO19.14119, CaO19.6827;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
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DR   EMBL; CP017625; AOW28683.1; -; Genomic_DNA.
DR   RefSeq; XP_719919.1; XM_714826.1.
DR   AlphaFoldDB; Q5ADL4; -.
DR   STRING; 237561.Q5ADL4; -.
DR   PRIDE; Q5ADL4; -.
DR   GeneID; 3638501; -.
DR   KEGG; cal:CAALFM_C306770WA; -.
DR   CGD; CAL0000178025; SLU7.
DR   VEuPathDB; FungiDB:C3_06770W_A; -.
DR   eggNOG; KOG2560; Eukaryota.
DR   HOGENOM; CLU_019317_3_0_1; -.
DR   InParanoid; Q5ADL4; -.
DR   OMA; RWYGYST; -.
DR   OrthoDB; 816947at2759; -.
DR   PRO; PR:Q5ADL4; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR   InterPro; IPR021715; Slu7_dom.
DR   InterPro; IPR039974; Splicing_factor_SLU7.
DR   PANTHER; PTHR12942; PTHR12942; 1.
DR   Pfam; PF11708; Slu7; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..350
FT                   /note="Pre-mRNA-splicing factor SLU7"
FT                   /id="PRO_0000218544"
FT   REGION          28..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   350 AA;  41024 MW;  FAF921C321713E15 CRC64;
     MPKYQPKNGE LNPYIPRYIL ETPRYQQDII NKSPEQEDAQ DQTTTAHDPL AHQRKTGEII
     DNSIAQSGTG IKDEFKGTIR VEENESYDSK RDRWYGYSTE EWLTHLKNWN DKKQSRKHAS
     AQDNDDSDDT DYELELIELE LDKKDMKKNI KKDPMEKMLR DRQDIPAYIY NITSNPNNKI
     RIEYDPKSRL AKDSAKGFLN KRNQFVKKLT GDGDELMKLQ KMAQELDNEH EKDRKLAKLK
     QEFYGEENPK TVPQTDLSLS LEASPTLMML KSKQLQNEKL AKSIQSKQEV MEKYNASTES
     DEKESKKTGH LEDKLFLNHK YIYGSYYENG KWGYKCCKQF DKNSRCTATD