ID   SLU7_CANGA              Reviewed;         318 AA.
AC   Q6FRY5;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Pre-mRNA-splicing factor SLU7;
GN   Name=SLU7; OrderedLocusNames=CAGL0H04917g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
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DR   EMBL; CR380954; CAG59942.1; -; Genomic_DNA.
DR   RefSeq; XP_447009.1; XM_447009.1.
DR   AlphaFoldDB; Q6FRY5; -.
DR   SMR; Q6FRY5; -.
DR   STRING; 5478.XP_447009.1; -.
DR   EnsemblFungi; CAG59942; CAG59942; CAGL0H04917g.
DR   GeneID; 2888505; -.
DR   KEGG; cgr:CAGL0H04917g; -.
DR   CGD; CAL0132000; CAGL0H04917g.
DR   VEuPathDB; FungiDB:CAGL0H04917g; -.
DR   eggNOG; KOG2560; Eukaryota.
DR   HOGENOM; CLU_072877_0_0_1; -.
DR   InParanoid; Q6FRY5; -.
DR   OMA; KSKMFRR; -.
DR   Proteomes; UP000002428; Chromosome H.
DR   GO; GO:0071021; C:U2-type post-spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR   GO; GO:0000386; F:second spliceosomal transesterification activity; IEA:EnsemblFungi.
DR   GO; GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IEA:EnsemblFungi.
DR   InterPro; IPR021715; Slu7_dom.
DR   InterPro; IPR039974; Splicing_factor_SLU7.
DR   PANTHER; PTHR12942; PTHR12942; 1.
DR   Pfam; PF11708; Slu7; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..318
FT                   /note="Pre-mRNA-splicing factor SLU7"
FT                   /id="PRO_0000218545"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          37..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        6..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..299
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   318 AA;  37458 MW;  CAE5630671B1DFCB CRC64;
     MHNKKVTKDE KKNTKTKDVN EHIPNYIKNL PWYYQDIDKN SKNNSKEQDY LRHHRQRRDD
     KTIDIDNNDQ AKIGTGIKDE FEVIVENKKT TIDGIIKRRK DEKDWDARKD RWYGYSGKEY
     EEVLKKWEKS REDLNNTTEE SAYDTDEEIE MMKLGLTPKD LEQNIKGSSV RLREDKAAYL
     KDIYSSTTNY DPKSRLYKSD DLGSIDEHSN MFLRHLTGEG KELNDLNKFA RENAKESGIR
     DELVDADKVN HVLVANPTKL EVLRKQKELD SLKLTEEQNR QEQRKLKRKA KLLKKKAKKP
     KGTPQSDSTK AQLMDMYG